- CEO
- Osamu Okuda
- Full Time Employees
- 5,026
- Sector
- Healthcare
- Industry
- Drug Manufacturers - General
- Address
- 2-1-1 Nihonbashi-Muromachi Chuo Japan 103-8324
- IPO Date
- Aug 3, 2012
- Business
- Chugai Pharmaceutical Co., Ltd. Chugai Pharmaceutical Co., Ltd. (CHGCF) is a research and development-focused pharmaceutical company that engages in the research, development, manufacturing, marketing, importation, and exportation of prescription pharmaceuticals, primarily in oncology, immunology, neurology, nephrology, and other specialty areas; its main products include oncology offerings such as Alecensa (alectinib, ALK inhibitor), Avastin (bevacizumab, anti-VEGF humanized monoclonal antibody), Herceptin (trastuzumab, anti-HER2 humanized monoclonal antibody), Kadcyla (trastuzumab emtansine, anti-HER2 antibody-tubulin polymerization inhibitor conjugate), Lunsumio (mosunetuzumab, anti-CD20/CD3 humanized bispecific antibody), Perjeta (pertuzumab, anti-HER2 humanized monoclonal antibody), Phesgo (pertuzumab, trastuzumab and vorhyaluronidase alfa combination), Polivy (polatuzumab vedotin, antimicrotubule binding anti-CD79b monoclonal antibody), and Tecentriq (atezolizumab, anti-PD-L1 humanized monoclonal antibody), as well as specialty products like Actemra (tocilizumab, humanized anti-human IL-6 receptor monoclonal antibody), CellCept (mycophenolate mofetil, immunosuppressant), Edirol (eldecalcitol, osteoporosis agent), Enspryng (satralizumab, pH-dependent binding humanized anti-IL-6 receptor monoclonal antibody), Evrysdi (risdiplam, spinal muscular atrophy agent), Hemlibra (emicizumab, anti-coagulation factor IXa/X humanized bispecific monoclonal antibody), Mircera (epoetin beta pegol, long-acting erythropoiesis-stimulating agent), PiaSky (crovalimab, pH-dependent binding humanized anti-complement C5 monoclonal antibody), Tamiflu (oseltamivir, anti-influenza agent), and Vabysmo (faricimab, anti-VEGF/anti-Ang-2 bispecific antibody), supported by advanced antibody engineering technologies and genomic profiling tools like FoundationOne CDx. Founded in 1925 and headquartered in Tokyo, Japan, the company operates domestically through manufacturing and R&D in Japan and internationally with sales and production in Europe, China, Taiwan, South Korea, and over 110 countries approving its products, functioning as a subsidiary of Roche Holding Ltd. with a strategic alliance since 2002 that enhances its global R&D and market access. Recent developments include a collaboration and license agreement with Rani Therapeutics in October 2025 for up to $1.085 billion to develop oral biologics using RaniPill technology for rare diseases and immunology, targeting multiple high-value therapeutics; the acquisition of Renalys Pharma, Inc. announced on October 24, 2025, for approximately 15 billion yen upfront plus earn-outs to secure exclusive rights to sparsentan (FILSPARI) for IgA nephropathy in Japan, South Korea, and Taiwan, followed by a planned absorption-type merger effective December 29, 2025, to integrate operations and accelerate kidney disease pipeline advancement alongside its existing sefaxersen project.