Defence Therapeutics Inc.
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- Defence Therapeutics Inc. (CSE: DTC; OTCQB: DTCFF; FSE: DTC), a pre-clinical Canadian biotechnology company headquartered in Montreal, Quebec, develops the proprietary Accum platform to enhance intracellular drug delivery for biologics targeting cancer and infectious diseases. Founded in 2017 and formerly known as Accum Therapeutics Inc., the company focuses on oncology solutions including Accum-enhanced antibody-drug conjugates (ADCs) that boost potency up to 60-fold while reducing toxicity and dosing requirements; radio-immuno conjugates (rADCs) combining ADC precision with radioactive payloads such as Actinium-225 for solid tumors; the AccuTOX program, dimers of Accum with independent anti-cancer activity cleared for Phase I trials in melanoma by Health Canada and eligible for FDA studies; ARM-X mesenchymal stem cell-based cancer vaccines; Accuvac dendritic cell vaccines; protein-based formulations against COVID-19 and infectious diseases; and mRNA vaccination programs. Defence Therapeutics operates primarily in Canada with a global IP portfolio of eight granted US patents and pursues partnerships for ADC and radiopharma licensing worldwide. Recent developments include a fully subscribed CAD 2 million debenture financing in September 2025; formation of a Scientific Advisory Board in December 2025 to advance Accum-enhanced ADCs; an ongoing collaboration with Canadian Nuclear Laboratories on Actinium-225 radiotherapeutics; and a 50:50 joint venture with Orano to develop rADCs; alongside strategic outreach to ADC developers following presentations at the World ADC Conference and CPHI in 2025.
Company News
Defence Therapeutics Wins Best Poster Award and Takes Center Stage at World ADC San Diego 2026, a Key Recognition in the Field Highlighting the Potential of Its Accum Platform
Defence Therapeutics Inc. (OTCMKTS:DTCFF) Stock Short Interest Report for September
Defence Therapeutics to Take the Stage at World ADC San Diego to Discuss the Next Frontier in Antibody-Drug Conjugates
Defence Therapeutics Appoints Finance Executive Sherry Aulin to Its Board of Directors
Defence Therapeutics Provides Corporate Update as Company Executes on Strategic Priorities
Defence Therapeutics CEO Highlights Recent Progress and Outlines Strategic Priorities in Letter to Shareholders
Defence Therapeutics Provides Updates on Sharing Agreement
Defence Therapeutics Expands Radiopharmaceutical Development Strategy with Alpha and Beta-Emitter Programs
Defence Therapeutics Strengthens Radiopharmaceutical Leadership with Appointment of Dr. Ryan Simms as Chief Operating Officer and Head of Radiopharmaceutical Programs
Defence Therapeutics Appoints Dr. Amie Phinney as President and Chief Executive Officer
Defence Therapeutics Opens New Office in Hamilton to Expand Its Accum Radiopharmaceutical Platform
Defence Therapeutics to Participate in Bio International Convention 2026 Next Week for Strategic Partnership Discussions
Defence Therapeutics Appoints Seasoned Biopharmaceutical Executive Dr John Beaver to Its Board of Directors
Defence Therapeutics Appoints Antibody Drug Conjugates Pioneer Dr. John Lambert to Its Board of Directors
Defence Therapeutics Strengthens Its Scientific Advisory Board with the Appointment of Dr. Sarkis Meterissian
Defence Therapeutics Enhances In-House ADC Development Platform with Expanded Analytical and Cellular Testing Capabilities
Defence Therapeutics Announces Grant of Restricted Stock Units
Defence Therapeutics Announces Warrant Terms Amendment
Defence Therapeutics Announces Closing of Private Placement of Units for Gross Proceeds of $9,595,000
Defence Therapeutics to Showcase Accum Platform at Key International Industry Events in March