- Business
- EoCene Ltd. is a biopharmaceutical and medical device company headquartered in Ramat Gan, Israel, that develops and seeks to commercialize therapies and technologies for gastrointestinal disease management, GI oncology and related therapeutic areas. Founded as Galmed Pharmaceuticals Ltd., the company operates through a diversified platform that includes Colospan Ltd., a wholly owned commercial-stage medical device subsidiary; its flagship CG-100 intraluminal bypass device for colorectal surgery; and its therapeutic portfolio led by Aramchol, a synthetic fatty acid-bile acid conjugate being evaluated across liver disease and oncology applications, including gastrointestinal cancers. The company’s products and services include the development of prescription therapeutics; medical devices designed to protect colorectal anastomoses and reduce diverting stomas; investigational and commercial-readiness support for device and drug programs; and related clinical development, regulatory and commercialization activities, with operations and strategic collaborations spanning Israel, Europe and the United States. In September 2026, the company rebranded from Galmed Pharmaceuticals to EoCene Ltd., changed its Nasdaq ticker from GLMD to EOCN, launched a new corporate website, regained compliance with Nasdaq’s minimum bid price requirement, and terminated its $20 million standby equity purchase agreement with Yorkville after drawing about $7.3 million; it also reported that the rebranding follows the June 2026 acquisition of Colospan and reflects its strategic shift from a liver-focused biotech toward a GI-focused medtech and biopharmaceutical platform. The company states that CG-100 has FDA Breakthrough Device Designation, CE marking under EU MDR and FDA IDE authorization for investigational use in the United States, while its broader development pipeline continues to include Aramchol and other GI-oriented initiatives.