Genfit S.A., a biopharmaceutical firm, is dedicated to discovering and advancing therapeutic compounds and diagnostic innovations for significant metabolic and hepatic disorders. The company's lead compound, Iqirvo (elafibranor), has recently gained accelerated approval from the U.S. FDA in June 2024, followed by European Medicines Agency and MHRA approvals in September 2024, for the treatment of primary biliary cholangitis. Ipsen holds the global licensing rights for elafibranor, providing Genfit with milestone payments and royalties. Additionally, Genfit develops the NIS4 technology, a non-invasive blood test for identifying at-risk non-alcoholic steatohepatitis (NASH) and fibrosis, which powers Labcorp's commercially available NASHnext diagnostic. The pipeline also includes several programs focused on acute-on-chronic liver failure (ACLF), such as G1090N in Phase 1, and preclinical assets like SRT-015, CLM-022, and VS-02-HE, while development of VS-01 in ACLF was discontinued and is being re-prioritized for urea cycle disorder. Genfit also progresses GNS561, an investigational therapy for cholangiocarcinoma, through a collaboration with Genoscience Pharma. Established in 1999, Genfit S.A. is headquartered in Loos, France, and voluntarily delisted its American Depositary Shares from Nasdaq in November 2025.