SeaStar Medical Holding Corporation
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- SeaStar Medical Holding Corporation (Nasdaq: ICU) is a commercial-stage medical technology company that develops and commercializes proprietary extracorporeal therapies to reduce the consequences of hyperinflammation on vital organs in critically ill patients. The company offers the Selective Cytopheretic Device (SCD), a disease-modifying platform therapy that neutralizes over-active neutrophils and monocytes to halt cytokine storms and destructive immune responses; QUELIMMUNE, an FDA-approved SCD therapy for pediatric patients with acute kidney injury (AKI) due to sepsis/septic shock requiring continuous renal replacement therapy (CRRT); and NEUTRALIZE-AKI, an SCD therapy in pivotal clinical trials for adult patients with AKI requiring CRRT, with FDA Breakthrough Device Designation for multiple indications including cardiorenal syndrome, hepatorenal syndrome and myocardial stunning in end-stage renal disease. Founded in 2007 and headquartered in Denver, Colorado, SeaStar Medical operates primarily in the United States, targeting ICU patients with acute and chronic inflammatory conditions through integration with existing CRRT circuits and regional citrate anticoagulation. Recent developments include raising approximately $12.4 million in gross proceeds through equity offerings in June, July and August 2025 to extend its financial runway into 2026 and support SCD advancement; completing interim analysis of the NEUTRALIZE-AKI trial showing early favorable safety and efficacy trends; expanding trial sites to meet 2026 enrollment targets; reporting Q3 2025 net revenue of $183,000 with ongoing QUELIMMUNE sales growth; and implementing cost-saving measures to focus resources on the adult AKI market, which is 50 times larger than the pediatric segment.
SeaStar Medical Supports Advances in Critical Care of Pediatric Patients with Acute Kidney Injury (AKI)
SeaStar Medical Announces New ICD-10-PCS Codes for Its SCD Therapy for Acute Kidney Injury
SeaStar Medical to Present at Upcoming Investor Summit Conference
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SeaStar Medical Showcases New Positive Data from the QUELIMMUNE SAVE Registry and an Analysis of the Unique Immunomodulatory Mechanism of the SCD Therapy at AKI & CRRT 2026
SeaStar Medical Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Updates
SeaStar Medical to Report Fourth Quarter and Year-End 2025 Financial Results on March 25, 2026
SeaStar Medical to Present at the Life Sciences Investor Forum on March 11th
SeaStar Medical Announces Completion of FDA Enrollment Requirement for SAVE Surveillance Registry Evaluating QUELIMMUNE Safety for Pediatric AKI
Short Interest in SeaStar Medical Holding Corporation (NASDAQ:ICU) Rises By 85.5%