Idorsia Ltd

Idorsia Ltd

IDRSF
Idorsia LtdUS flagOther OTC
5.75
USD
- -
- -
1.47BMarket Cap
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
1.37
0.48
0.18
0.5
0.21
0.55
0.85
0.62
1.03
1.15
Basic EPS, GAAP
-2.78
-0.12
-3.06
-3.81
-3.11
-3.77
-4.67
-1.67
-1.45
-0.52
-0.71
Free Cash Flow per Basic Share
-2.25
0.76
-2.9
-3.72
-2.62
-3.68
-4.99
-3.58
-2.13
-0.78
-1.39
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-2.73
-0.07
-3.12
-6.86
-9.38
-11.71
-15.98
-17.58
-18.62
-16.33
-17.7
Tangible Book Value per Share
4.21
6.39
5.18
1.26
4.1
0.58
-3.81
-5.45
-6.77
-5.43
-6.2
Basic Weighted Avg Shares
121
116
126
129
143
168
177
178
182
215
189
Sales/Revenue/Turnover
- -
158
61
24
72
35
97
152
113
221
217
Operating Margin (%)
- -
-4.99
-612.15
-2,027.71
-572.18
-1,734.15
-826.93
-356.37
-299.76
-52.76
-79.66
Depreciation Expense
18
10
20
20
19
18
20
19
18
17
19
Net Income, GAAP
-335
-14
-386
-494
-445
-635
-828
-298
-264
-112
-133
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
0.62
Profit Margin (%)
- -
-9.03
-637.42
-2,072.33
-619.85
-1,795.23
-852.6
-195.5
-234.43
-50.64
-61.36
Working Capital
687
788
837
665
907
912
426
-25
-188
63
-94
LT Debt
293
365
571
623
630
1,153
1,218
998
1,048
1,260
1,092
Total Equity
508
740
658
164
585
104
-661
-969
-1,212
-1,137
-1,142
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
9.29
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Dec'24
Mar'25
Jun'25
ST Debt
209
208
211
LT Borrowings
932
932
982
LT Finance Leases
116
113
110
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
188
203
204
Market Capitalization
138
176
360

Working Capital

FRC

in mil. unless spec.
Dec'24
Mar'25
Jun'25
Total Current Assets
255
186
249
Cash, Cash Equivalents & STI
124
65
82
Accounts Receivable, Net
26
34
34
Inventories
63
62
67
Total Current Liabilities
443
327
344
Payables & Accruals
- -
- -
- -
ST Debt
209
208
211
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
-150.2%
-6.19%
Free Cash Flow
- -
-3.07%
-56.97%
Net Income, GAAP
- -
-12%
-57.65%
Sales/Revenue/Turnover
- -
50.16%
96.06%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
10
16
26
60
113
2025
59
72
48
- -
221
2026
57
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
0.17
- -
- -
- -
-1.45
2025
0.33
- -
- -
- -
-0.52
2026
-0.18
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Jean-Paul Clozel
Full Time Employees
1,100
Sector
Healthcare
Industry
Biotechnology
Address
Hegenheimermattweg 91 Allschwil Switzerland 4123
IPO Date
Jul 17, 2017
Business
Idorsia Ltd, a biopharmaceutical company headquartered in Allschwil, Switzerland and founded in 2017 following its demerger from Actelion, discovers, develops and commercializes small-molecule drugs targeting central nervous system disorders, cardiovascular conditions, immunology, orphan diseases and infectious diseases; key marketed products include QUVIVIQ (daridorexant), a dual orexin receptor antagonist for insomnia commercially available in the US, Germany, Italy, Switzerland, Spain, the UK, Canada, Austria, France, Sweden and Finland with approval throughout the EU, and TRYVIO (aprocitentan) in the US and JERAYGO (aprocitentan) in the EU and UK, both dual endothelin receptor antagonists for resistant hypertension in combination with other antihypertensives; the pipeline features lucerastat, a glucosylceramide synthase inhibitor for Fabry disease in Phase 3 open-label extension with kidney biopsy data expected in Q2 2025, daridorexant for pediatric insomnia in Phase 2 with readout in Q2 2026, early-stage assets such as IDOR-1117-2520 (CCR6 antagonist) for psoriasis, ACT-777991 (CXCR3 antagonist) for vitiligo and ACT-1004-1239 (ACKR3 antagonist) for progressive multiple sclerosis advancing to proof-of-concept studies, and a synthetic glycan vaccine platform including IDOR-1134-2831 for Clostridioides difficile in Phase 1 with results in mid-2026. Operations span North America, Europe and partnerships in Asia-Pacific; partnered programs include selatogrel for acute myocardial infarction and cenerimod for systemic lupus erythematosus outlicensed worldwide to Viatris in March 2024 with amended terms in February 2025 reducing Idorsia's development cost contribution by USD 100 million while retaining royalties, aprocitentan seeking new global partners after FDA approval in March 2024 and EU approval in June 2024, daridorexant licensed to Simcere for Greater China with launch in Hong Kong and to Nxera for Asia-Pacific excluding China, and other collaborations such as with the US Department of Defense for PTSD and Owkin for immuno-oncology. Recent developments encompass QUVIVIQ net sales of CHF 61 million in 2024 with expansion via partnerships like Menarini in France and Berlin-Chemie in Germany, a holistic restructuring of CHF 800 million convertible bond debt in February 2025 securing CHF 150 million new funding to extend runway into 2026, workforce reductions to 552 permanent employees by early 2025 for cost efficiency targeting commercial profitability in 2026, and ongoing prioritization of the pipeline for inflection points or out-licensing.

Company News

APIChat
  • Idorsia reports new positive results with its breakthrough C. difficile vaccine – underscoring the unique potential of its glycan technology

  • New analysis of Idorsia's aprocitentan demonstrates significant and sustained reduction in albuminuria in patients with uncontrolled / resistant hypertension

  • Shareholders vote in favor of all proposals by the Board at Idorsia's Annual General Meeting 2026

  • Idorsia reports strong Q1 2026 performance with 74% QUVIVIQ sales growth year-on-year

  • Idorsia issues invitation to the 2026 Annual General Meeting of Shareholders

  • Idorsia welcomes Amer Joseph as new Chief Medical Officer and Head of Global Clinical Development

  • Idorsia Ltd (IDRSF) Discusses Positive Phase II Results for Daridorexant in Pediatric Insomnia and Neurodevelopmental Disorders Transcript

  • Idorsia announces the nomination of three candidates for election to the Board of Directors

  • Idorsia announces management change

  • Idorsia expands QUVIVIQ's global footprint through new partnership with Pharmalink

  • Idorsia Ltd (IDRSF) Q4 2025 Earnings Call Transcript

  • Idorsia reports strong 2025 results with QUVIVIQ sales more than doubling – further sales growth ahead with multiple pipeline catalysts in 2026

  • Invitation to Idorsia's FY 2025 Financial Reporting webcast and conference call

  • Idorsia to present long-term lucerastat data and kidney biopsy results at WORLDSymposium

  • Global expansion of Idorsia's QUVIVIQ continues with EMS partnership for Latin America

  • Idorsia Ltd (IDRSF) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript

  • Idorsia to present at J.P. Morgan 2026 Healthcare Conference

  • Nature Communications reports promising effect of Idorsia's lucerastat on kidney function in Fabry disease

  • Idorsia initiates a proof-of-concept trial with its oral first-in-class selective CCR6 antagonist

  • Idorsia's daridorexant in women during menopausal transition age with insomnia