Kiniksa Pharmaceuticals International, plc
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- Kiniksa Pharmaceuticals International, plc (KNSA) is a commercial-stage biopharmaceutical company that discovers, acquires, develops and commercializes therapeutic medicines for patients with debilitating diseases featuring significant unmet medical needs, with a primary focus on cardiovascular and inflammatory indications worldwide. The company markets ARCALYST (rilonacept), an interleukin-1 alpha and beta inhibitor approved for treating recurrent pericarditis, an inflammatory cardiovascular disease; its pipeline includes vixarelimab, a monoclonal antibody in Phase 2b trials for chronic inducible urticaria and other pruritic skin diseases; KPL-387, a preclinical Fc-modified immunoglobulin G2 monoclonal antibody that received FDA Orphan Drug Designation for pericarditis; and other early-stage candidates targeting unmet needs in immunology and beyond. Founded in 2015 and headquartered in London, United Kingdom, with primary U.S. operations in Lexington, Massachusetts, the company maintains additional facilities in Zug, Switzerland, and La Jolla, California, supporting global development and commercialization efforts. In June 2024, Kiniksa Pharmaceuticals, Ltd. changed its name to Kiniksa Pharmaceuticals International, plc to reflect its expanded international presence; recent highlights include robust ARCALYST net product revenue growth of 61% year-over-year to $180.9 million in Q3 2025, raised full-year 2025 sales guidance to $560-$580 million, a return to profitability with $18.4 million net income in Q3 2025, and pipeline advancement via FDA Orphan Drug Designation for KPL-387 in pericarditis.
Company News
Kiniksa Highlights ARCALYST Growth as KPL-387 Advances Into Phase 3
Kiniksa Pharmaceuticals to Present at Canaccord Genuity 46th Annual Growth Conference
KNSA Q2 Earnings Call Backs Higher ARCALYST Sales Outlook
Earnings Estimates Rising for Kiniksa Pharmaceuticals International, plc (KNSA): Will It Gain?
Kiniksa Pharmaceuticals International, plc (KNSA) Q2 2026 Earnings Call Transcript
Kiniksa Pharmaceuticals International Q2 Earnings Call Highlights
Kiniksa Pharmaceuticals International, plc (KNSA) Q2 Earnings Match Estimates
Kiniksa Pharmaceuticals Reports Second Quarter 2026 Financial Results and Recent Portfolio Execution
Kiniksa Pharmaceuticals Reports Second Quarter 2026 Financial Results and Recent Portfolio Execution
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