Nektar Therapeutics
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- Nektar Therapeutics (Nasdaq: NKTR), a biopharmaceutical company, discovers, develops and commercializes therapies that selectively modulate the immune system to treat autoimmune disorders, inflammatory conditions and cancer; its lead product candidate, rezpegaldesleukin (REZPEG), is a regulatory T cell stimulator in Phase 2b clinical development for atopic dermatitis, alopecia areata and new-onset Type 1 diabetes, with FDA Fast Track designation granted for severe-to-very-severe alopecia areata in 2025; the company's immuno-oncology pipeline features NKTR-255, an engineered IL-15 receptor agonist evaluated in ongoing trials in combination with checkpoint inhibitors, TIL therapy and CAR-T therapies for solid tumors and hematological malignancies; preclinical programs include NKTR-0165, a TNFR2 agonist antibody for multiple sclerosis, vitiligo and ulcerative colitis with a planned first-in-human study in 2026, NKTR-0166, a TNFR2 bispecific antibody for rheumatic diseases, and NKTR-422, a CSF1R agonist for inflammation resolution. Founded in 1990 and headquartered in San Francisco, California, Nektar Therapeutics operates primarily in the United States with global clinical trial activities and partnerships extending internationally; the company leverages proprietary polymer conjugate technologies and immunology expertise to enhance drug pharmacokinetics, efficacy and patient convenience across autoimmune, inflammatory and oncology segments, targeting patients with unmet needs in immune-mediated diseases. Recent developments include completion of enrollment in the REZOLVE-AA Phase 2b trial for rezpegaldesleukin in alopecia areata and REZOLVE-AD trial data presentations at EADV and ACAAI 2025 meetings demonstrating statistical significance in endpoints for atopic dermatitis; in early 2025, Nektar initiated a Phase 2 trial agreement with TrialNet for rezpegaldesleukin in Type 1 diabetes and advanced IND-enabling studies for NKTR-0165 and NKTR-0166; the company completed a $115 million public offering and ATM proceeds to bolster its balance sheet, while selling royalties on CIMZIA and MIRCERA to Royalty Pharma in a non-dilutive transaction, and Ampersand Capital Partners acquired its PEGylation reagent manufacturing business in late 2024.
Company News
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Nektar Therapeutics: Downgrade To Hold On REZPEG Market Outlook Setback And More
Nektar Therapeutics (NKTR) Shareholder/Analyst Call Transcript
Nektar REZPEG Data Show Durable Hair Regrowth, Set Up Phase III Alopecia Trial
Nektar Stock Sinks Despite Promising Hair Loss Treatment Data
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New Rezpegaldesleukin Data Supporting Long-term Durability and Disease Improvement in Patients with Alopecia Areata and Atopic Dermatitis at EADV Congress 2026
Nektar Therapeutics (NASDAQ:NKTR) Stock Rated “Moderate Buy” by Sell-Side Brokerages
New Biomarker Data Presented in a Late Breaking Oral Presentation at EADV Congress 2026 Showing Early Molecular Responses to Rezpegaldesleukin Across Multiple Immune Pathways Dysregulated in Patients
New Biomarker Data Presented in a Late Breaking Oral Presentation at EADV Congress 2026 Showing Early Molecular Responses to Rezpegaldesleukin Across Multiple Immune Pathways Dysregulated in Patients with Atopic Dermatitis
Nektar Announces Three Oral Presentations for Rezpegaldesleukin at the European Academy of Dermatology & Venereology (EADV) Congress 2026
Nektar Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
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HB Wealth Management LLC Purchases New Position in Nektar Therapeutics $NKTR
Nektar Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Nektar Announces Publication in The Lancet of Positive Phase 2b REZOLVE-AD 16-Week Induction Results of Rezpegaldesleukin in Moderate-to-Severe Atopic Dermatitis
Nektar: Maintaining 'Strong Buy' Rating Due To REZPEG Catalyst, Another Coming