Ono Pharmaceutical Co., Ltd.

Ono Pharmaceutical Co., Ltd.

OPHLY
Ono Pharmaceutical Co., Ltd.US flagOther OTC
4.95
USD
+0.02
- -
6.98BMarket Cap
Ono Pharmaceutical Co., Ltd.
OPHLY
(Other OTC)

Recent

price

4.95

P/E

ratio

- -

div

yld

- -

ROIC.AI

2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
TTM
FRC
83.34
91.67
89.8
90.08
85.39
100.79
153.94
168.35
187.12
193.39
206.53
242.6
305.24
349.03
345.48
365.89
172
Revenue per Share
14.92
15.32
14.41
12.79
8.16
15.71
35.09
32.33
33.41
39.48
50.37
54.06
76.94
88.86
35.51
49.49
37.71
Basic EPS, GAAP
17.56
12.33
7.16
9.79
0.29
-0.78
31.68
-9.07
24.1
34.2
35.85
33.27
99.05
62.37
52.84
59.27
43.71
Free Cash Flow per Basic Share
12.05
11.98
11.98
11.99
11.99
11.98
12.65
15.05
14.15
15.06
14.99
18.57
20.3
25.82
26.62
26.62
13.49
Dividend per Share
279.06
296.02
297
298.01
293.71
295.76
320.46
306.91
334.81
358.42
400.19
444.51
496.4
545.44
573.54
601.16
571.3
Book Value per Share
242.54
254.55
266.42
269.8
277.52
275.38
301.2
304.7
323.94
331.72
381.59
400.76
463.25
514.74
310.08
340.8
297.02
Tangible Book Value per Share
1,623
1,590
1,590
1,590
1,590
1,590
1,590
1,555
1,543
1,512
1,498
1,490
1,465
1,440
1,409
1,410
1,418
Basic Weighted Avg Shares
135,255
145,778
142,806
143,247
135,775
160,284
244,797
261,836
288,634
292,420
309,284
361,361
447,187
502,672
486,871
515,785
243,960
Sales/Revenue/Turnover
26.03
26
20.96
18.45
10.9
19.03
29.53
23.18
21.48
26.5
31.79
28.56
31.75
31.82
12.27
17.88
25.78
Operating Margin (%)
3,051
3,005
4,765
5,109
6,100
6,534
7,821
9,213
10,621
14,214
15,820
17,721
17,451
18,140
26,894
37,752
9,054
Depreciation Expense
24,222
24,360
22,919
20,344
12,976
24,979
55,793
50,284
51,539
59,704
75,425
80,519
112,723
127,977
50,047
69,767
53,485
Net Income, GAAP
33.66
38.43
29.73
30.28
27.8
24.28
24.82
21.16
20.67
24.85
25.17
23.18
21.33
21.8
15.44
24.55
16.94
Effective Tax Rate (%)
17.91
16.71
16.05
14.2
9.56
15.58
22.79
19.2
17.86
20.42
24.39
22.28
25.21
25.46
10.28
13.53
21.92
Profit Margin (%)
165,172
155,488
170,497
167,285
162,868
171,379
188,100
140,995
111,467
133,893
153,909
215,340
222,172
309,972
306,808
304,663
276,750
Working Capital
12
222
484
468
317
515
542
320
1,765
6,173
7,030
6,501
6,678
6,552
113,500
82,468
128,788
LT Debt
394,572
424,841
442,541
451,724
475,213
476,255
524,211
529,618
562,736
568,022
639,743
661,674
747,813
798,605
788,202
856,644
788,110
Total Equity
5.72
5.58
4.76
4.07
2.27
4.78
10.51
8.79
8.78
9.89
11.64
11.83
15.26
15.43
5.71
7.15
5.86
Return on Invested Capital (%)
5.27
5.17
4.76
4.22
2.69
5.27
11.24
10.05
10.23
11.14
12.9
12.56
15.96
16.61
6.18
7.47
6.1
Return on Capital (%)
5.38
5.27
4.86
4.3
2.76
5.33
11.39
10.19
10.37
11.28
13.22
12.77
16.23
16.92
6.28
8.43
6.71
Return on Common Equity (%)

Capital Structure

FRC

in mil. unless spec.
Mar'24
Jun'25
Sep'25
ST Debt
2,310
- -
32,869
LT Borrowings
- -
- -
120,000
LT Finance Leases
6,552
- -
8,788
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
470
- -
470
Market Capitalization
1,193,164
1,047,104
893,000

Working Capital

FRC

in mil. unless spec.
Mar'24
Jun'25
Sep'25
Total Current Assets
413,596
- -
401,410
Cash, Cash Equivalents & STI
204,595
- -
181,134
Accounts Receivable, Net
136,066
- -
137,291
Inventories
48,629
- -
52,154
Total Current Liabilities
103,624
- -
124,660
Payables & Accruals
- -
- -
- -
ST Debt
2,310
- -
32,869
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
6.15%
6.12%
8.68%
Free Cash Flow
-446.85%
28.43%
12.2%
Net Income, GAAP
19.69%
7.76%
39.4%
Sales/Revenue/Turnover
13.28%
11.16%
5.94%
Total Cash Common Dividend
7.48%
11.34%
0.04%

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
120,016
138,697
131,191
112,769
502,672
2025
- -
- -
- -
- -
486,871
2026
- -
- -
- -
- -
515,785

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
21.72
29.39
25.25
- -
88.86
2025
- -
- -
- -
- -
35.51
2026
- -
- -
- -
- -
49.49

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
11.48
0.84
12.68
- -
25.82
2025
- -
- -
- -
- -
26.62
2026
- -
- -
- -
- -
26.62
Business
Ono Pharmaceutical Co., Ltd. is a Japan-based pharmaceutical company primarily engaged in the production, purchase, and sale of prescription and over-the-counter pharmaceuticals and diagnostic reagents. Founded in 1717 and headquartered in Chuo-ku, Osaka, Japan, the company offers a broad portfolio of products including oral drugs, injectable medicines, and patch formulations. Core products cover oncology therapies such as the anti-cancer drugs Velexbru, Braftovi, and Mektovi; treatments for catecholamine excess secretion like Demser; and a variety of prescription medicines targeting multiple therapeutic areas. Ono Pharmaceutical focuses heavily on research and development to innovate and deliver new drugs globally. In recent years, Ono Pharmaceutical has made significant strategic expansions, including the acquisition of US-based Deciphera Pharmaceuticals in April 2024 for approximately $2.4 billion, enhancing its oncology portfolio with Deciphera’s kinase inhibitor QINLOCK® (ripretinib), approved in over 40 countries for gastrointestinal stromal tumors. The acquisition strengthens Ono’s presence in the United States and Europe and accelerates its kinase drug discovery research. Additionally, the company has entered a co-development and marketing collaboration with Seikagaku for Gel-One, a treatment for osteoarthritis, and launched new clinical trials and therapies including povetacicept, a breakthrough therapy for kidney diseases. Ono also opened a new office in Zug, Switzerland in late 2025 to support growth in Europe and partner markets. The company continues active collaborations with biotech firms and research institutions to advance drug discovery, especially in oncology, immunology, neurology, and specialty medicines. Ono operates globally, with significant focus on Japan, the United States, and European markets. Its product pipeline includes small molecule drugs, monoclonal antibodies, synthetic peptides, and bispecific antibodies, with several drugs recently receiving FDA approvals. Subsidiaries include Deciphera Pharmaceuticals, functioning as a fully owned oncology-focused entity. Ono Pharmaceutical’s strategic direction emphasizes innovative cancer therapeutics, immunotherapies, and specialty medicines, maintaining its long-standing commitment to fighting disease and pain while expanding its global footprint through acquisitions, partnerships, and new product launches.

Company News

APIChatGPT
  • Ono Pharma Announces Oral Presentation of New Data from the Phase 2 Clinical Study of ONO-4578 (EP4 antagonist) in Certain Gastric Cancers at the ASCO 2026 Annual Meeting

  • Ono Pharma Announces New Drug Discovery Collaboration with Congruence Therapeutics in the Priority Areas of Neurology and Immunology

  • Deciphera Pharmaceuticals Announces U.S. Food and Drug Administration Acceptance for Filing of New Drug Application for Tirabrutinib in Patients with Relapsed or Refractory PCNSL

  • Ono Pharmaceutical Co., Ltd. (OPHLY) Presents at 44th Annual J.P.

  • Ono Pharmaceutical Co., Ltd. (OPHLF) Q1 FY2025 Earnings Call Transcript

  • Ono Pharmaceutical Co., Ltd. (OPHLF) Q1 2024 Earnings Call Transcript

  • Japan's Ono Pharma says $2.4 bln Deciphera purchase 'first step' for global expansion

  • ONO to buy Deciphera Pharmaceuticals at a huge premium

  • ONO to buy Deciphera Pharmaceuticals at a huge premium

  • Deciphera Catapults 72% After Ono Pharmaceutical Agrees To Buy It For $2.4 Billion

  • Japan's ONO Pharmaceutical to buy Deciphera for $2.4 billion

  • Ono Pharmaceutical Co. (OPHLF) Upgraded to Buy: Here's Why