- Business
- Otsuka Holdings Co., Ltd. operates as a holding company overseeing a global group engaged in pharmaceuticals, nutraceuticals, consumer products, and other businesses worldwide. The company develops and markets pharmaceutical products in psychiatry, neurology, oncology, cardiovascular and renal systems, digestive systems, ophthalmology, diagnostics, intravenous solutions, and medical devices; nutraceuticals and consumer products including Pocari Sweat ion supply drink, Calorie Mate nutritional food, Equelle women's health supplements, Body-mainte conditioning foods and beverages, and OS-1 oral rehydration solution; and other offerings such as soft drinks, wines, functional foods, clinical testing equipment, cosmetics, chemical products including hydrazine and potassium titanate, IT solutions, bio-pesticides, infusion and clinical nutrition products, stable isotopes, and polyolefin foams. Founded in 1921 with the holding company established in 2008, Otsuka Holdings is headquartered in Tokyo, Japan, with principal operations in Japan, the United States, Europe, and Asia. Recent developments include the acquisition of Jnana Therapeutics Inc. in 2024 to bolster its pipeline in phenylketonuria and autoimmune diseases through Otsuka America Inc., the formation of a joint venture with ICU Medical Inc. in late 2024 for North American IV solutions manufacturing effective early 2025 under Otsuka Pharmaceutical Factory, and the submission of a new drug application to the U.S. FDA in November 2025 for centanafadine to treat ADHD in children.