Sutro Biopharma, Inc.
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- Sutro Biopharma, Inc. (NASDAQ: STRO), a clinical-stage oncology company, develops site-specific and novel-format antibody drug conjugates (ADCs) for cancer using its proprietary cell-free protein synthesis platforms, XpressCF and XpressCF+; core wholly owned product candidates include STRO-004, a tissue factor-targeting ADC for solid tumors such as cervical, lung and breast cancers with U.S. FDA IND clearance received in November 2025 and first-in-human dosing on track before year-end, STRO-006, a highly selective integrin beta-6 ADC for multiple solid tumors advancing toward clinical development in 2026, and a wholly owned dual-payload ADC program combining cytotoxic and immunostimulatory payloads with IND submission targeted for 2027; additional programs encompass STRO-001 targeting CD74 for multiple myeloma and non-Hodgkin lymphoma, STRO-002 (luveltamab tazevibulin) targeting folate receptor-alpha for ovarian and endometrial cancers, and STRO-003 targeting ROR1. Founded in 2003 and headquartered in South San Francisco, California, the company operates primarily in the United States with a global collaboration pipeline including partnerships with Astellas on dual-payload immunostimulatory ADCs where one program entered IND-enabling toxicology in early 2025, Ipsen on STRO-003 which Ipsen opted not to advance in 2025, Merck on cytokine derivatives, and a manufacturing partnership with VGXI for luvelta production; recent developments feature a strategic portfolio review and organizational restructuring announced in March and September 2025 prioritizing ADC programs, cessation of San Carlos manufacturing facility operations by year-end 2025, leadership transition with Jane Chung assuming CEO role from Bill Newell in March 2025 and Greg Chow appointed CFO in June 2025, entry into a research collaboration with the U.S. FDA in July 2025 to advance ADC regulatory standards, and preclinical data presentations at conferences including World ADC and SITC in November 2025 highlighting dual-payload ADCs' potential to overcome resistance.
Company News
Sutro Biopharma Appoints Lucas Donigian as Senior Vice President, Business Development
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Sutro Biopharma Reports Second Quarter 2026 Financial Results and Provides Early Update on STRO-004 Phase 1 Study
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Sutro Biopharma Presents Promising Preclinical Data Across its Pipeline of Next-Generation Single and Dual-Payload ADC Programs at AACR 2026
Sutro Biopharma (NASDAQ:STRO) Trading 10.4% Higher on Analyst Upgrade
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Sutro Biopharma Reports Full Year 2025 Financial Results and Business Highlights
Sutro Biopharma, Inc. (NASDAQ:STRO) Receives Consensus Rating of “Hold” from Analysts
Sutro Biopharma: ADC Developer With Poor Track Record Aims For Positive 2026
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Sutro Biopharma Announces Pricing of $110.0 million Underwritten Offering
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Sutro Biopharma, Inc. (STRO) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript
Sutro Biopharma, Inc. (NASDAQ:STRO) Given Average Recommendation of “Hold” by Analysts