- CEO
- Ei Yamada
- Full Time Employees
- 55
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- Saito Bio-Incubator Ibaraki Japan 567-0085
- IPO Date
- Jul 3, 2017
- Business
- AnGes, Inc. is a Japanese biopharmaceutical company specializing in the research, development, and marketing of gene-based medicines and gene therapy products. Its core products include hepatocyte growth factor (HGF) gene therapy for ischemic diseases such as chronic arterial occlusive disease; NF-κB decoy oligonucleotides for chronic discogenic lumbar back pain; DNA vaccines; and hemagglutinating virus of Japan envelope (HVJ-E) non-viral vectors. The company also develops genome editing technology platforms and products through its consolidated subsidiary EmendoBio Inc., expanding its capabilities in advanced gene therapy. AnGes operates primarily in Japan, the United States, and other international markets, supported by subsidiaries including AnGes USA, Inc. and EmendoBio Inc., both headquartered in Jersey City, New Jersey. Founded in December 1999 and headquartered in Ibaraki, Japan, AnGes focuses its business segments on nucleic acid medicine and genomic drug discovery targeting intractable, rare diseases, and diseases lacking effective treatments.
Recent major developments include the FDA granting Breakthrough Therapy designation in 2024 for its flagship HGF gene therapy product. The company is actively developing a Tie2 tyrosine kinase receptor agonist (AV-001) for viral and bacterial-associated pneumonia and continuing advancement of NF-κB decoy oligonucleotide treatments. Strategic expansions include the acquisition of EmendoBio Inc. in December 2020 to strengthen genome editing technology and the establishment of new R&D bases, including in the U.S. Additionally, AnGes has engaged in strategic alliances, such as co-development partnerships with Vasomune Therapeutics for COVID-19/ARDS therapeutics and MyBiotics Pharma for microbiome-related treatments. These initiatives underscore AnGes' commitment to advancing innovative gene-based medicines for global markets.