Annexon, Inc.

Annexon, Inc.

ANNX
Annexon, Inc.US flagNASDAQ Global Select
4.01
USD
+0.60
- -
657.01MMarket Cap
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
Basic EPS, GAAP
-1.6
-2.83
-3.74
-3.4
-2.6
-1.77
-1.01
-1.33
-1.13
Free Cash Flow per Basic Share
-1.5
-2.18
-3.16
-2.81
-2.25
-1.6
-0.86
-1.2
-1.07
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-2.05
-3.21
9.02
6.01
4.84
3.2
2.68
1.42
1.07
Tangible Book Value per Share
-2.05
-3.21
9.02
6.01
4.84
3.2
2.68
1.42
1.07
Basic Weighted Avg Shares
11
13
17
38
55
76
137
155
180
Sales/Revenue/Turnover
- -
- -
- -
- -
- -
- -
- -
- -
- -
Operating Margin (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
Depreciation Expense
- -
- -
1
2
2
2
2
2
2
Net Income, GAAP
-18
-37
-63
-130
-142
-134
-138
-207
-203
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
Working Capital
42
40
343
226
226
246
286
200
174
LT Debt
- -
- -
- -
33
32
29
26
23
22
Total Equity
38
44
344
232
231
251
293
212
186
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
-45.24
-61.3
-55.73
-50.84
-81.9
-105.26

Capital Structure

FRC

•

in mil. unless spec.
Dec'25
Mar'26
Jun'26
ST Debt
3
3
3
LT Borrowings
- -
- -
- -
LT Finance Leases
23
22
22
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
149
163
175
Market Capitalization
750
900
997

Working Capital

FRC

•

in mil. unless spec.
Dec'25
Mar'26
Jun'26
Total Current Assets
242
228
213
Cash, Cash Equivalents & STI
238
225
209
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
43
36
38
Payables & Accruals
32
30
31
ST Debt
3
3
3
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

•

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
-7.08%
-27.79%
Free Cash Flow
- -
33.86%
58.02%
Net Income, GAAP
- -
32.3%
49.56%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.21
-0.23
-0.25
-0.33
-1.01
2025
-0.37
-0.33
-0.37
-0.28
-1.33
2026
-0.23
-0.28
- -
- -
- -

Quarterly Dividends Per Share

FRC

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

CEO
Douglas E. Love
Full Time Employees
92
Sector
Healthcare
Industry
Biotechnology
Address
1400 Sierra Point Parkway Brisbane CA United States of America 94005
IPO Date
Jul 24, 2020
Business
Annexon, Inc. is a clinical-stage biopharmaceutical company engaged in discovering and developing novel therapies targeting neuroinflammatory and autoimmune diseases via complement pathway inhibition. Founded in 2017 and headquartered in Brisbane, California, Annexon focuses on treating classical complement-mediated diseases affecting the brain, body, and eye. Its core product pipeline includes ANX005, an investigational monoclonal antibody in a pivotal Phase III trial for Guillain-Barré Syndrome; ANX007, an antigen-binding fragment in Phase III trials for geographic atrophy in dry age-related macular degeneration; ANX1502, an oral small molecule for autoimmune indications; and ANX009, a C1q-blocking fragment designed for subcutaneous delivery. The company develops and anticipates commercializing therapies primarily in the autoimmune, neurodegeneration, and ophthalmology sectors targeting rare, high-unmet medical needs. Its product candidates undergo late-stage clinical development with dosing modalities including intravenous, intravitreal, and oral administration. Annexon operates primarily in the United States but aims for regulatory approvals and commercialization potential in both the U.S. and Europe. Recent major developments include the initiation and ongoing enrollment of pivotal Phase III trials for ANX007 in geographic atrophy, planning head-to-head trials against market competitors such as SYFOVRE® (pegcetacoplan), and preparing for Biologics License Application filings for ANX005 based on clinical data anticipated by late 2024. In 2025, the company launched a $75 million public offering to support continued advancement of its neuroinflammatory treatment pipeline and expanded strategic investor interest through Nuveen LLC’s acquisition of a minority stake aligned with its high-yield resilience investment strategy. Annexon also plans to present focused R&D updates highlighting the therapeutic potential of its portfolio. Annexon sustains its business through strategic clinical program progression and investment support aimed at delivering transformative therapies for debilitating complement-driven diseases. This description summarizes Annexon's role as a clinical-stage biotechnology firm with a detailed focus on complement inhibition platforms and its recent financial and strategic developments in the last 1-2 years.

Company News

  • Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

  • Annexon: Preserving Patient Function Is The Real Investment Opportunity

  • Annexon to Present Patient Baseline Characteristics from Vonaprument Phase 3 ARCHER II Pivotal Trial for Geographic Atrophy at The Retina Society 59th Annual Scientific Meeting

  • Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

  • Annexon to Participate in Upcoming September Investor Conferences

  • Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

  • Annexon, Inc. (ANNX) Q2 2026 Earnings Call Transcript

  • Annexon Q2 Earnings Call Highlights

  • Annexon Reports Second Quarter 2026 Financial Results, Business Updates and Key Anticipated Milestones

  • Annexon Expands Vonaprument Phase 3 Program in Geographic Atrophy with Addition of Month 24 Dual Primary Endpoint Complementing Month 15 Primary Endpoint and Launch of Open-Label Extension Study

  • Annexon Reports First U.S. and European Patient Cohort of GBS FORWARD Study Demonstrated Rapid, Positive Clinical Responses in All Tanruprubart Treated Patients Within One Week

  • Annexon Secures Strategic Credit Facility for up to $200 Million from Oxford Finance

  • Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

  • Annexon to Present Phase 2 ARCHER Baseline Characteristics Associated with Confirmed Best Corrected Visual Acuity 15-Letter Loss in Patients with Geographic Atrophy at ASRS 2026

  • Annexon: Perfect Complement To A Speculative Biotech Portfolio

  • Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

  • Annexon, Inc. (ANNX) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript

  • Annexon Eyes ‘Win Season' With Q4 Vision Trial Data, GBS Filings Ahead

  • Annexon Maps 3 Big Pipeline Catalysts Ahead of Q4 Vision-Drug Readout

  • Annexon to Participate in Upcoming June Investor Conferences