- CEO
- Paul Goddard
- Full Time Employees
- 56
- Sector
- Healthcare
- Industry
- Drug Manufacturers - Specialty & Generic
- Address
- 6300 Dumbarton Circle Fremont CA United States of America 94555
- IPO Date
- Nov 7, 2007
- Business
- ARYx Therapeutics, Inc. (ARYX) is a biopharmaceutical company that discovers and develops novel therapies for large, chronic disease markets using its proprietary RetroMetabolic Drug Design technology to create structurally unique molecules that mimic the efficacy of established drugs while avoiding specific safety liabilities through safer metabolic pathways. The company focuses on orally administered treatments for conditions including gastrointestinal disorders, atrial fibrillation, thrombosis risk, and psychiatric disorders; its historical clinical-stage product candidates have included ATI-7505 (a prokinetic agent for chronic constipation, gastroparesis, functional dyspepsia, irritable bowel syndrome with constipation, and gastroesophageal reflux disease), budiodarone (previously ATI-2042, an oral anti-arrhythmic for atrial fibrillation), tecarfarin (previously ATI-5923, an oral anticoagulant for patients at risk of dangerous blood clots), and ATI-9242 (a next-generation atypical antipsychotic for schizophrenia and other psychiatric conditions). Founded in 1997 and headquartered in Fremont, California, ARYx Therapeutics operates primarily in the United States with a pipeline targeting patients requiring chronic oral therapies.
In recent years, the company has maintained a development focus on its core pipeline amid limited public updates, with historical advancements including a $35 million committed equity financing facility secured in 2009 to support partnering activities for its advanced compounds and a $30.4 million Series E financing completed in 2006 to advance three clinical programs through Phase 2 proof-of-concept. ARYx Therapeutics went public via IPO in November 2007 and trades on OTC markets under the ARYX ticker, employing approximately 56 full-time staff as of recent profiles. No major acquisitions, new product launches, or strategic alliances have been publicly reported in the last 1-2 years, reflecting a low-profile operational status typical for development-stage biopharma firms reliant on partnerships for commercialization.