Anavex Life Sciences Corp.

Anavex Life Sciences Corp.

AVXL
Anavex Life Sciences Corp.US flagNASDAQ Global Select
2.56
USD
+0.14
- -
236.78MMarket Cap
Anavex Life Sciences Corp.
AVXL
(NASDAQ Global Select)

Recent

price

2.56

P/E

ratio

- -

div

yld

- -

ROIC.AI

2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
TTM
FRC
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Revenue per Share
-1.64
-1.16
-1.18
-0.46
-1.02
-0.65
-0.42
-0.33
-0.39
-0.54
-0.45
-0.54
-0.62
-0.6
-0.52
-0.54
-0.46
Basic EPS, GAAP
-0.86
-0.6
-0.24
-0.1
-0.27
-0.23
-0.26
-0.22
-0.28
-0.38
-0.37
-0.44
-0.32
-0.35
-0.37
-0.46
-0.39
Free Cash Flow per Basic Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Dividend per Share
-4.08
-4.64
-5.32
-5.16
-5.22
-3.4
-2.22
-2.24
-2.4
-2.73
-2.74
-2.83
-3.19
-3.67
-4.03
-4.48
-4.49
Book Value per Share
-0.55
-0.18
-0.41
-0.31
0.02
0.69
0.18
0.59
0.5
0.41
0.47
2.16
1.85
1.78
1.44
1.11
1.47
Tangible Book Value per Share
5
6
7
8
10
19
35
41
45
49
58
70
77
80
83
85
86
Basic Weighted Avg Shares
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Sales/Revenue/Turnover
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Operating Margin (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Depreciation Expense
-9
-7
-8
-4
-10
-12
-15
-13
-17
-26
-26
-38
-48
-48
-43
-46
-40
Net Income, GAAP
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
-3
-1
-3
-2
6
13
6
24
22
20
27
151
142
142
120
95
127
Working Capital
- -
- -
- -
1
6
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
LT Debt
-3
-1
-3
-2
- -
13
6
24
22
20
27
151
142
142
120
95
127
Total Equity
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)

Capital Structure

FRC

in mil. unless spec.
Jun'25
Sep'25
Dec'26
ST Debt
- -
- -
- -
LT Borrowings
- -
- -
- -
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
85
87
93
Market Capitalization
785
759
307

Working Capital

FRC

in mil. unless spec.
Jun'25
Sep'25
Dec'26
Total Current Assets
102
104
133
Cash, Cash Equivalents & STI
101
103
132
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
11
9
6
Payables & Accruals
9
7
4
ST Debt
- -
- -
- -
Deferred Revenue
1
1
1

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
66.23%
82.28%
-21.12%
Free Cash Flow
29.26%
14.95%
26.72%
Net Income, GAAP
16.18%
13.64%
7.85%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.11
-0.13
-0.14
- -
-0.52
2025
-0.14
-0.13
-0.16
-0.11
-0.54
2026
-0.06
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -
Business
Anavex Life Sciences Corp. is a clinical-stage biopharmaceutical company focused on the development of innovative small molecule therapeutics for the treatment of central nervous system (CNS) diseases, including Alzheimer's disease, Parkinson’s disease dementia, schizophrenia, and rare neurodevelopmental disorders such as Rett syndrome. The company's core product is ANAVEX®2-73 (blarcamesine), an orally available Sigma-1 receptor (SIGMAR1) and muscarinic receptor agonist designed to restore cellular homeostasis by targeting protein misfolding, mitochondrial dysfunction, and autophagy processes. Anavex’s precision medicine platform leverages proprietary SIGMACEPTOR™ technology to develop scalable treatments that potentially modify disease progression across a range of neurodegenerative and neurodevelopmental disorders. The company’s clinical pipeline includes completion of multiple Phase 2 and Phase 3 trials for ANAVEX®2-73 in Alzheimer's disease, Parkinson’s disease dementia, and Rett syndrome, with ongoing plans for further pivotal studies including schizophrenia-related disorders. Recently, Anavex has entered a strategic partnership with Partex NV, leveraging Partex’s proprietary artificial intelligence technology to enhance its precision medicine drug development platform and patient experience ecosystem, extending beyond R&D into healthcare sales and marketing. In 2025, Anavex reported positive clinical trial results demonstrating continued long-term benefit of oral blarcamesine in early Alzheimer's disease patients with notable cognitive and biomarker improvements compared to natural history controls. The company is actively pursuing regulatory re-examination following a negative initial opinion from the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) regarding the marketing authorization application for blarcamesine. Other ongoing development milestones include advancing ANAVEX®3-71 for schizophrenia-related disorders and designing Phase 2/3 trials for Fragile X syndrome. Anavex maintains a commitment to precision medicine approaches and patient-centric innovation across its geographic operations primarily focused in the United States and Europe. Founded in 2005 and headquartered in New York, Anavex Life Sciences operates as a publicly traded company listed on NASDAQ under the ticker AVXL. The company targets underserved patient populations with high unmet medical needs in neurodegenerative and neurodevelopmental CNS disorders, aiming to bring novel treatment paradigms through its orally administered small molecule therapies. This description reflects the company's current product focus, strategic alliances, regulatory activities, clinical pipeline developments, and operational status as of late 2025.

Company News

APIChatGPT
  • Anavex Life Sciences Receives Expected Nasdaq Delinquency Notification

  • Anavex Life Sciences Board of Directors Appoints Former Senior Vice President of Clinical Development Terrie Kellmeyer, PhD, as Interim Chief Executive Officer

  • Anavex Life Sciences Highlights New Scientific Findings on Shared Biology Between Autism and Alzheimer's Disease

  • Anavex Life Sciences to Present at the 25th Annual Needham Virtual Healthcare Conference

  • Anavex Life Sciences Provides Comprehensive Regulatory Update

  • INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Anavex Life Sciences Corp. - AVXL

  • Anavex Life Sciences Stock Crushed As European Alzheimer's Drug Filing Pulled After EMA Pushback

  • Anavex Life Sciences Provides Update on Regulatory Review in the EU for Blarcamesine to Treat Early Alzheimer's Disease

  • Anavex Life Sciences Presents New Data from its AD-004 Phase IIb/III Trial at AD/PD 2026 Conference Demonstrating Consistent Correlation Between the Treatment Effect of Oral Blarcamesine and Preservation of Brain Volume in Early Alzheimer's Disease

  • New Scientific Findings Highlight Hypothesis of Autophagy Failure as a Precursor of Amyloid Beta and Tau Pathology in Alzheimer's Disease

  • Anavex Life Sciences Presents Significant Treatment Effects of Blarcamesine in New Advanced Alpha-Synuclein Model of Parkinson's Disease at AD/PD 2026 Conference

  • Anavex Life Sciences to Present at the Citizens Life Sciences Conference

  • Anavex Life Sciences to Present at the 46th TD Cowen Annual Health Care Conference

  • Anavex Life Sciences Appoints Seasoned Healthcare Leader to Board of Directors

  • Anavex Life Sciences (AVXL) Upgraded to Buy: Here's What You Should Know

  • Is Anavex Life Sciences (AVXL) Stock Outpacing Its Medical Peers This Year?

  • Anavex Life Sciences Corp. (AVXL) Q1 2026 Earnings Call Transcript

  • Anavex Life Sciences Reports Fiscal 2026 First Quarter Financial Results and Provides Business Update

  • Anavex Life Sciences to Announce Fiscal 2026 First Quarter Financial Results on Monday, February 9, 2026

  • Anavex Life Sciences Highlights Oral Alzheimer’s Drug Blarcamesine, Precision Strategy at JPM Conference