BioCryst Pharmaceuticals, Inc.

BioCryst Pharmaceuticals, Inc.

BCRX
BioCryst Pharmaceuticals, Inc.US flagNASDAQ Global Select
8.34
USD
-0.23
- -
1.75BMarket Cap
BioCryst Pharmaceuticals, Inc.
BCRX
(NASDAQ Global Select)

Recent

price

8.34

P/E

ratio

- -

div

yld

- -

ROIC.AI

2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
TTM
FRC
1.4
0.44
0.53
0.31
0.2
0.66
0.36
0.3
0.2
0.42
0.11
0.88
1.46
1.72
2.18
4.17
4.06
Revenue per Share
-0.76
-1.26
-0.79
-0.55
-0.68
-0.59
-0.75
-0.78
-0.98
-0.94
-1.09
-1.03
-1.33
-1.18
-0.43
1.26
-2.1
Basic EPS, GAAP
-0.65
-0.72
-0.76
-0.48
-0.58
-0.25
-0.8
-0.49
-0.9
-0.78
-0.81
-0.81
-0.88
-0.51
-0.26
1.64
1.42
Free Cash Flow per Basic Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Dividend per Share
-6.64
-7.82
-7.93
-7.64
-7
-7
-7.67
-7.47
-7.08
-7.26
-6.11
-6.73
-7.81
-8.74
-8.55
-7.17
-10.2
Book Value per Share
1.47
0.33
-0.01
-0.02
1.13
0.65
0.02
0.99
0.48
0.33
-0.12
-0.6
-1.58
-2.37
-2.3
-0.57
-2.54
Tangible Book Value per Share
45
45
49
55
67
73
74
84
103
116
167
179
186
192
207
210
218
Basic Weighted Avg Shares
62
20
26
17
14
48
26
25
21
49
18
157
271
331
451
875
886
Sales/Revenue/Turnover
-53.42
-252.44
-122.2
-177.24
-336.35
-81.74
-184.45
-227.95
-456.2
-203.66
-981.12
-113.08
-54.81
-31.29
-0.56
38.98
-43.11
Operating Margin (%)
2
1
1
- -
- -
- -
- -
1
1
1
1
1
1
2
1
1
2
Depreciation Expense
-34
-57
-39
-30
-45
-43
-55
-66
-101
-109
-183
-184
-247
-227
-89
264
-458
Net Income, GAAP
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
1.32
22.48
Effective Tax Rate (%)
-54.27
-289.91
-148.64
-173.72
-332.08
-89.15
-209.25
-261.18
-490.25
-222.99
-1,026.35
-117.11
-91.24
-68.36
-19.72
30.16
-51.71
Profit Margin (%)
59
27
25
27
32
2
13
51
45
72
218
462
411
346
262
208
178
Working Capital
- -
30
30
30
- -
2
25
20
28
45
248
591
739
822
806
437
815
LT Debt
66
15
- -
-1
76
48
2
84
49
38
-19
-107
-295
-456
-476
-119
-554
Total Equity
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
103.13
- -
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
-33.76
-53.46
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
2
2
3
LT Borrowings
633
427
802
LT Finance Leases
10
10
12
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
211
213
254
Market Capitalization
1,586
1,637
2,078

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
356
404
374
Cash, Cash Equivalents & STI
213
275
238
Accounts Receivable, Net
91
107
109
Inventories
5
5
6
Total Current Liabilities
190
196
195
Payables & Accruals
124
65
130
ST Debt
2
2
3
Deferred Revenue
- -
- -
5

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
551.28%
122.99%
-74.96%
Free Cash Flow
-45.1%
-163.05%
-748.99%
Net Income, GAAP
-25.42%
-86.21%
-396.87%
Sales/Revenue/Turnover
101.23%
201.43%
94.1%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
93
109
117
132
451
2025
146
163
159
407
875
2026
156
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.17
-0.06
-0.07
-0.13
-0.43
2025
- -
0.02
0.06
1.17
1.26
2026
-2.98
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -
Business
BioCryst Pharmaceuticals, Inc. is a biotechnology company specializing in the development and commercialization of oral small-molecule and protein therapeutics primarily targeting rare diseases. The company's core products include ORLADEYO (berotralstat), an oral plasma kallikrein inhibitor used for the prophylaxis and treatment of hereditary angioedema (HAE) in adults and pediatric patients 12 years and older; RAPIVAB (peramivir injection), an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated influenza; and various pipeline candidates such as BCX9930, an oral Factor D inhibitor for complement-mediated diseases, and BCX9250, an oral ALK-2 inhibitor for fibrodysplasia ossificans progressiva (FOP). BioCryst's commercial offerings focus on rare genetic and complement system diseases, with ongoing clinical programs advancing novel therapies for conditions including Netherton syndrome and diabetic macular edema (DME). Founded in 1986 and headquartered in Durham, North Carolina, BioCryst operates globally, with a strategic emphasis on expanding access to its therapies worldwide. The company targets specialty healthcare providers and patients afflicted by rare and serious conditions, leveraging advanced medicinal chemistry and biological sciences to deliver transformative oral and injectable drugs. Recent major company developments include the completion of the sale of its European ORLADEYO business as part of a strategic refocus on core markets, and ongoing regulatory activities such as the FDA's review of ORLADEYO oral granules for pediatric use with an expected decision in December 2025. This pediatric indication expansion aims to broaden the accessible patient population significantly. BioCryst also reported a robust revenue increase driven by ORLADEYO, projecting full-year 2024 revenues of approximately $450.7 million and targeting profitability milestones by the end of 2025. The company is advancing its pipeline with clinical data expected in 2025 from programs such as BCX17725 for Netherton syndrome and avoralstat for DME. Additionally, BioCryst entered a $700 million acquisition deal for Astria, underscoring its commitment to deepening its rare disease portfolio. BioCryst continues to emphasize a people-focused approach alongside scientific innovation to meet unmet medical needs in hereditary angioedema and other rare disease areas. Its goal is to sustain strong growth of ORLADEYO while diversifying its pipeline toward market expansion and long-term profitability.

Company News

APIChat
  • BioCryst to Present New HAE Data from ORLADEYO® (berotralstat) and Navenibart at the 2026 European Academy of Allergy and Clinical Immunology Annual Meeting

  • BioCryst to Present New Real-World Evidence Underscoring the Ongoing Burden of Pediatric Hereditary Angioedema at ISPOR 2026

  • BioCryst Pharmaceuticals, Inc. (BCRX) Presents at Bank of America Global Healthcare Conference 2026 Transcript

  • These Analysts Revise Their Forecasts On BioCryst Pharma After Q1 Earnings

  • BioCryst Pharmaceuticals, Inc. (BCRX) Q1 2026 Earnings Call Transcript

  • BioCryst Pharmaceuticals (BCRX) Reports Q1 Loss, Beats Revenue Estimates

  • BioCryst Reports First Quarter 2026 Financial Results and Provides Business Update

  • BioCryst Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

  • BioCryst Announces European Licensing Agreement with Irish Affiliate of Neopharmed Gentili for Navenibart in Hereditary Angioedema

  • BioCryst to Present at Upcoming Investor Conferences

  • BioCryst to Report First Quarter 2026 Financial Results on May 6

  • BioCryst Appoints Sandeep M. Menon Chief Research and Development Officer

  • BioCryst Pharmaceuticals (NASDAQ:BCRX) & Polydex Pharmaceuticals (OTCMKTS:POLXF) Head to Head Analysis

  • BioCryst Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

  • Assenagon Asset Management S.A. Lowers Holdings in BioCryst Pharmaceuticals, Inc. $BCRX

  • BioCryst Pharmaceuticals, Inc. $BCRX Shares Sold by JPMorgan Chase & Co.

  • Alkeon Capital Management LLC Trims Position in BioCryst Pharmaceuticals, Inc. $BCRX

  • Avoro Capital Advisors LLC Trims Stock Position in BioCryst Pharmaceuticals, Inc. $BCRX

  • BioCryst Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

  • BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) Given Consensus Recommendation of “Moderate Buy” by Brokerages