BioCryst Pharmaceuticals, Inc.

BioCryst Pharmaceuticals, Inc.

BCRX
BioCryst Pharmaceuticals, Inc.US flagNASDAQ Global Select
9.96
USD
-0.13
- -
2.53BMarket Cap
BioCryst Pharmaceuticals, Inc.
BCRX
(NASDAQ Global Select)

Recent

price

9.96

P/E

ratio

- -

div

yld

- -

ROIC.AI

2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
TTM
FRC
1.4
0.44
0.53
0.31
0.2
0.66
0.36
0.3
0.2
0.42
0.11
0.88
1.46
1.72
2.18
4.17
4.1
Revenue per Share
-0.76
-1.26
-0.79
-0.55
-0.68
-0.59
-0.75
-0.78
-0.98
-0.94
-1.09
-1.03
-1.33
-1.18
-0.43
1.26
-1.68
Basic EPS, GAAP
-0.65
-0.72
-0.76
-0.48
-0.58
-0.25
-0.8
-0.49
-0.9
-0.78
-0.81
-0.81
-0.88
-0.51
-0.26
1.64
1.63
Free Cash Flow per Basic Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Dividend per Share
1.46
0.32
-0.01
-0.02
1.05
0.65
0.02
0.85
0.45
0.25
-0.11
-0.58
-1.57
-2.21
-2.28
-0.56
-1.78
Book Value per Share
1.46
0.32
-0.01
-0.02
1.05
0.65
0.02
0.85
0.45
0.25
-0.11
-0.58
-1.57
-2.21
-2.28
-0.56
-1.78
Tangible Book Value per Share
45
45
49
55
67
73
74
84
103
116
167
179
186
192
207
210
229
Basic Weighted Avg Shares
62
20
26
17
14
48
26
25
21
49
18
157
271
331
451
875
941
Sales/Revenue/Turnover
-53.42
-252.44
-122.2
-177.24
-336.35
-81.74
-184.45
-227.95
-456.2
-203.66
-981.12
-113.08
-54.81
-31.29
-0.56
38.98
-33.29
Operating Margin (%)
2
1
1
- -
- -
- -
- -
1
1
1
1
1
1
2
1
1
2
Depreciation Expense
-34
-57
-39
-30
-45
-43
-55
-66
-101
-109
-183
-184
-247
-227
-89
264
-385
Net Income, GAAP
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
1.32
2.23
Effective Tax Rate (%)
-54.27
-289.91
-148.64
-173.72
-332.08
-89.15
-209.25
-261.18
-490.25
-222.99
-1,026.35
-117.11
-91.24
-68.36
-19.72
30.16
-40.9
Profit Margin (%)
59
27
25
27
32
2
13
51
45
72
218
462
411
346
262
208
276
Working Capital
- -
30
30
30
- -
2
25
20
28
45
248
591
739
822
806
437
790
LT Debt
66
15
- -
-1
76
48
2
84
49
38
-19
-107
-295
-456
-476
-119
-454
Total Equity
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
103.13
- -
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
104.73
39.84
Return on Capital (%)
-44.61
-141.82
- -
- -
- -
-69.75
-223.7
-154.16
-152.26
-248.94
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)

Capital Structure

FRC

in mil. unless spec.
Dec'25
Mar'26
Jun'26
ST Debt
2
3
3
LT Borrowings
427
802
778
LT Finance Leases
10
12
11
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
213
254
255
Market Capitalization
1,662
2,418
2,553

Working Capital

FRC

in mil. unless spec.
Dec'25
Mar'26
Jun'26
Total Current Assets
404
374
485
Cash, Cash Equivalents & STI
275
238
353
Accounts Receivable, Net
107
109
111
Inventories
5
6
6
Total Current Liabilities
196
195
209
Payables & Accruals
65
130
133
ST Debt
2
3
3
Deferred Revenue
- -
5
12

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
551.28%
122.99%
-74.96%
Free Cash Flow
-45.1%
-163.05%
-748.99%
Net Income, GAAP
-25.42%
-86.21%
-396.87%
Sales/Revenue/Turnover
101.23%
201.43%
94.1%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
93
109
117
132
451
2025
146
163
159
407
875
2026
156
218
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.17
-0.06
-0.07
-0.13
-0.43
2025
- -
0.02
0.06
1.17
1.26
2026
-2.98
0.31
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -
Business
BioCryst Pharmaceuticals, Inc. is a biotechnology company specializing in the development and commercialization of oral small-molecule and protein therapeutics primarily targeting rare diseases. The company's core products include ORLADEYO (berotralstat), an oral plasma kallikrein inhibitor used for the prophylaxis and treatment of hereditary angioedema (HAE) in adults and pediatric patients 12 years and older; RAPIVAB (peramivir injection), an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated influenza; and various pipeline candidates such as BCX9930, an oral Factor D inhibitor for complement-mediated diseases, and BCX9250, an oral ALK-2 inhibitor for fibrodysplasia ossificans progressiva (FOP). BioCryst's commercial offerings focus on rare genetic and complement system diseases, with ongoing clinical programs advancing novel therapies for conditions including Netherton syndrome and diabetic macular edema (DME). Founded in 1986 and headquartered in Durham, North Carolina, BioCryst operates globally, with a strategic emphasis on expanding access to its therapies worldwide. The company targets specialty healthcare providers and patients afflicted by rare and serious conditions, leveraging advanced medicinal chemistry and biological sciences to deliver transformative oral and injectable drugs. Recent major company developments include the completion of the sale of its European ORLADEYO business as part of a strategic refocus on core markets, and ongoing regulatory activities such as the FDA's review of ORLADEYO oral granules for pediatric use with an expected decision in December 2025. This pediatric indication expansion aims to broaden the accessible patient population significantly. BioCryst also reported a robust revenue increase driven by ORLADEYO, projecting full-year 2024 revenues of approximately $450.7 million and targeting profitability milestones by the end of 2025. The company is advancing its pipeline with clinical data expected in 2025 from programs such as BCX17725 for Netherton syndrome and avoralstat for DME. Additionally, BioCryst entered a $700 million acquisition deal for Astria, underscoring its commitment to deepening its rare disease portfolio. BioCryst continues to emphasize a people-focused approach alongside scientific innovation to meet unmet medical needs in hereditary angioedema and other rare disease areas. Its goal is to sustain strong growth of ORLADEYO while diversifying its pipeline toward market expansion and long-term profitability.

Company News

  • BioCryst to Present at Upcoming Investor Conference

  • Canada Pension Plan Investment Board Buys Shares of 115,805 BioCryst Pharmaceuticals, Inc. $BCRX

  • Is BioCryst Pharmaceuticals (BCRX) Stock Outpacing Its Medical Peers This Year?

  • BioCryst Pharmaceuticals: Owning Both Sides Of The HAE Preference Curve

  • Wall Street Analysts Think BioCryst (BCRX) Could Surge 108.21%: Read This Before Placing a Bet

  • BioCryst is profitable. Now it wants to buy more rare disease drugs

  • ADAR1 Capital Management LLC Takes $1.33 Million Position in BioCryst Pharmaceuticals, Inc. $BCRX

  • BioCryst Announces Approval of ORLADEYO® for Pediatric HAE Patients in Japan

  • BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) Receives Average Rating of “Moderate Buy” from Brokerages

  • Bank of America Corp DE Buys 3,556,208 Shares of BioCryst Pharmaceuticals, Inc. $BCRX

  • Assenagon Asset Management S.A. Buys 120,097 Shares of BioCryst Pharmaceuticals, Inc. $BCRX

  • Wall Street Analysts See a 98.74% Upside in BioCryst (BCRX): Can the Stock Really Move This High?

  • Implied Volatility Surging for BioCryst Pharmaceuticals Stock Options

  • A Profitable Rare-Disease Prize: Who Might Snap Up BioCryst?

  • BioCryst Pharmaceuticals, Inc. (BCRX) Q2 2026 Earnings Call Transcript

  • BioCryst Pharmaceuticals Q2 Earnings Call Highlights

  • BioCryst Pharmaceuticals (BCRX) Tops Q2 Earnings and Revenue Estimates

  • BioCryst Reports Second Quarter 2026 Financial Results

  • ADAR1 Capital Management LLC Has $1 Million Stock Holdings in BioCryst Pharmaceuticals, Inc. $BCRX

  • BioCryst to Report Second Quarter 2026 Financial Results on August 5