- CEO
- Robert Etherington
- Full Time Employees
- 75
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- 6550 South Millrock Drive Salt Lake City UT United States of America 84121
- IPO Date
- Oct 18, 2018
- Business
- Clene Inc. is a late clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics aimed at treating neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and Parkinson's disease. The company's core product pipeline includes CNM-Au8, an oral suspension of gold nanocrystals designed to restore neuronal health and function by enhancing cellular energy production and reducing oxidative stress; CNM-ZnAg, a broad-spectrum antiviral agent composed of silver and zinc nanocrystals targeting infectious diseases and wound healing; and CNM-AgZn17, a gel polymer suspension of zinc and silver ions also aimed at infectious disease treatment. Clene operates through its wholly owned subsidiary Clene Nanomedicine Inc., leveraging its electro-crystal-chemistry drug platform to produce stable nanocrystal suspensions for therapeutic use. Founded in 2020 and headquartered in Salt Lake City, Utah, Clene serves a global biopharmaceutical market focused on high unmet medical needs in neurodegenerative and infectious diseases.
Recent major developments include the completion of FDA-recommended biomarker analyses for CNM-Au8 in ALS patients, demonstrating statistically significant reductions in disease biomarkers supporting potential disease-modifying effects. Clene plans to submit a New Drug Application (NDA) for CNM-Au8 under the FDA's accelerated approval pathway in the first quarter of 2026, with a Phase 3 RESTORE-ALS trial planned as the post-approval confirmatory study. The company hosted an investor call in December 2025 to update on the CNM-Au8 program and continues to invest in expanding its nanotherapeutics pipeline designed to improve mitochondrial health and protect neuronal function. Clene's technology platform and clinical-stage assets position it as an innovative player in the biotechnology sector with a focused strategy on addressing neurodegenerative and infectious diseases worldwide.