Curis, Inc.

Curis, Inc.

CRIS
Curis, Inc.US flagNASDAQ Global Market
0.51
USD
+0.00
- -
6.68MMarket Cap
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
18.22
11.45
6.39
5.67
6.64
6.3
6.03
4.45
2.33
2.18
1.89
1.73
- -
0.45
Basic EPS, GAAP
-14.96
-21.78
-47.81
-45.5
-35.75
-19.67
-19.37
-12.29
-9.92
-12.14
-8.96
-6.88
- -
-1.33
Free Cash Flow per Basic Share
-11.77
-19.66
-24.27
-27.22
-32.55
-18.21
-15.82
-10.86
-8.22
-11.73
-7.26
-6.27
- -
-1.83
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-922.96
-905.71
-678.66
-675.92
-638.31
-594.54
-612.8
-429.82
-238.38
-246.05
-226.01
-196.58
- -
-80.18
Tangible Book Value per Share
43.95
24.2
45.01
15.28
10.07
-8.14
-25.85
50
17.85
8.05
2.02
-2.38
- -
0.23
Basic Weighted Avg Shares
1
1
1
1
1
2
2
2
5
5
5
6
- -
16
Sales/Revenue/Turnover
15
10
8
8
10
10
10
11
11
10
10
11
9
7
Operating Margin (%)
-62.77
-161.15
-407.88
-532.08
-502.73
-281.29
-243.46
-229.79
-395.01
-521.75
-482.21
-408.34
-348.43
-485.12
Depreciation Expense
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Net Income, GAAP
-12
-19
-59
-60
-53
-33
-32
-30
-45
-57
-47
-43
-8
-21
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
-82.14
-190.28
-748.68
-802.59
-538.66
-312.38
-321.28
-276.03
-426.67
-557.69
-473.04
-397.77
-80.29
-299.66
Working Capital
54
42
75
35
50
15
18
163
109
82
39
7
-7
2
LT Debt
28
23
20
15
36
29
- -
5
4
3
1
2
- -
- -
Total Equity
45
30
65
29
24
-4
-34
131
91
47
20
-6
5
13
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
0.61
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
1
1
1
LT Borrowings
- -
- -
- -
LT Finance Leases
1
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
13
13
40
Market Capitalization
18
13
9

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
14
7
17
Cash, Cash Equivalents & STI
9
5
15
Accounts Receivable, Net
3
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
20
14
15
Payables & Accruals
9
13
12
ST Debt
1
1
1
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
-48.1%
-91.71%
-191.06%
Free Cash Flow
3.47%
5.97%
-31.25%
Net Income, GAAP
-8.72%
-6.14%
-82.53%
Sales/Revenue/Turnover
2.44%
-2.45%
-13.43%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
2
3
3
3
11
2025
2
3
3
1
9
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-2.05
-2.03
-1.7
-1.25
-6.88
2025
-1.25
-0.68
-0.49
1.23
- -
2026
-1.25
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
James E. Dentzer
Full Time Employees
34
Sector
Healthcare
Industry
Biotechnology
Address
Building C Lexington MA United States of America 02421
IPO Date
Aug 1, 2000
Website
curis.com
Business
Curis, Inc. Curis, Inc. (NASDAQ: CRIS) is a clinical-stage biotechnology company that discovers, develops and seeks to commercialize innovative small-molecule drug candidates targeting dysregulated signaling pathways in cancer, primarily focused on hematologic malignancies and select solid tumors; its lead product candidate is emavusertib (CA-4948), an orally available small-molecule inhibitor of IRAK4 kinase and FLT3 (in certain contexts), evaluated in multiple ongoing Phase 1/2 clinical trials including the TakeAim Lymphoma study in relapsed/refractory primary central nervous system lymphoma (PCNSL) in combination with ibrutinib, the TakeAim Leukemia study as monotherapy in relapsed/refractory acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (hrMDS), and frontline AML triplet combinations with venetoclax and azacitidine; the pipeline also includes fimepinostat (CUDC-907), an oral dual HDAC/PI3K inhibitor for MYC-altered cancers such as relapsed/refractory diffuse large B-cell lymphoma; immune checkpoint antagonists CA-327 (TIM3/PD-L1 bispecific) and CA-170 (VISTA/PD-L1 bispecific) for PDL1/TIM3- or PDL1/VISTA-expressing cancers; and royalty revenues from Erivedge (vismodegib, hedgehog pathway inhibitor) commercialized by Genentech, a member of the Roche Group, for advanced basal cell carcinoma. Founded in 2000 and headquartered in Lexington, Massachusetts, the company conducts operations primarily in the United States through preclinical research, clinical development, and strategic collaborations such as its 2015 exclusive license agreement with Aurigene Discovery Technologies Limited for emavusertib and related IRAK4 inhibitors. Recent developments include completion of enrollment in the TakeAim Leukemia Phase 1/2 monotherapy study with follow-up ongoing and initial data from the frontline AML triplet study showing 50% MRD conversion in evaluable patients; continued enrollment in TakeAim Lymphoma Parts B and C (BTKi-experienced and naïve PCNSL cohorts) to support potential accelerated approval filings in the US and EU, with updated PCNSL/SCNSL data presented at the 2025 Society for Neuro-Oncology meeting; filing of a protocol with the FDA and site activation for a new Phase 2 study of emavusertib plus BTKi in relapsed/refractory chronic lymphocytic leukemia (CLL) targeting complete remission, uMRD, and time-limited therapy, with first patient dosing expected late Q4 2025 or early Q1 2026 and data at ASH 2026; a $7.0 million registered direct offering and concurrent private placement in July 2025 extending cash runway into Q1 2026; and initial data from an investigator-sponsored Phase 1 study of emavusertib with gemcitabine/nab-paclitaxel in metastatic pancreatic ductal adenocarcinoma slated for ASCO GI 2026.

Company News

APIChat
  • Curis, Inc. (CRIS) Q1 2026 Earnings Call Transcript

  • Curis Provides First Quarter 2026 Business Update

  • Curis to Report First Quarter 2026 Financial and Operating Results and Host Conference Call and Webcast on May 12, 2026

  • Kiniksa Pharmaceuticals International, plc (KNSA) Tops Q1 Earnings and Revenue Estimates

  • Curis (CRIS) Upgraded to Buy: What Does It Mean for the Stock?

  • Curis, Inc. (CRIS) Q4 2025 Earnings Call Transcript

  • Curis Provides Fourth Quarter 2025 Business Update

  • SecurityBridge Releases the Cybersecurity Resilience Index for SAP (CRIS) to Set the Standard for SAP Security Maturity Benchmarking

  • Curis to Report Fourth Quarter 2025 Financial and Operating Results and Host Conference Call and Webcast on March 19, 2026

  • Head-To-Head Analysis: eXoZymes (NASDAQ:EXOZ) & Curis (NASDAQ:CRIS)

  • Curis Announces Closing of Private Placement Totaling up to $80.8 Million in Gross Proceeds

  • Curis Announces Pricing of Private Placement Totaling up to $80.8 Million in Gross Proceeds

  • Curis Provides Updated Data from its Frontline AML Triplet Study

  • Curis to Present at Upcoming 30th Annual SNO Meeting

  • Curis, Inc. (CRIS) Q3 2025 Earnings Call Transcript

  • Curis (CRIS) Reports Q3 Loss, Beats Revenue Estimates

  • Curis Provides Third Quarter 2025 Business Update

  • Curis to Report Third Quarter 2025 Financial and Operating Results and Host Conference Call and Webcast on November 6, 2025

  • Curis Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)

  • Curis, Inc. (CRIS) Presents At Cantor Global Healthcare Conference 2025 Transcript