- CEO
- N. Scott Fine
- Full Time Employees
- 8
- Sector
- Healthcare
- Industry
- Drug Manufacturers - Specialty & Generic
- Address
- 6714 NW 16th Street Gainesville FL United States of America
- IPO Date
- Dec 18, 2020
- Business
- Cyclo Therapeutics, Inc. (CYTHW) is a clinical-stage biotechnology company that develops cyclodextrin-based products for the treatment of neurodegenerative diseases; its lead candidate, Trappsol Cyclo (hydroxypropyl beta cyclodextrin), an orphan drug designated product, advances in a pivotal Phase 3 global TransportNPC trial for Niemann-Pick Disease Type C1, a rare fatal genetic disorder, with enrollment completed in May 2024 and interim analysis expected mid-2025, and in Phase IIb trials for Alzheimer's disease; the company also sells cyclodextrins and related products to pharmaceutical, nutritional, and other industries for diagnostics and specialty drugs. Incorporated in 1990 and headquartered in Gainesville, Florida, Cyclo Therapeutics operates primarily in the United States with global clinical trials and maintains an ongoing collaboration with the University of the Witwatersrand in Johannesburg to advance the Trappsol Cyclo platform and explore pipeline expansions. In March 2025, the company completed a merger with Rafael Holdings, Inc., its majority shareholder since strategic investments beginning in March 2023, which provided over $18 million in convertible debt funding since June 2024 to support operations and trial advancement; previously known as CTD Holdings, Inc., it rebranded to Cyclo Therapeutics in September 2019.