- CEO
- Robert E. Hoffman CPA
- Full Time Employees
- 2
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- United States of America
- Business
- DelMar Pharmaceuticals, Inc. (OTC: DMPWW) is a clinical-stage biopharmaceutical company focused on the development of novel cancer therapies for patients failing or resistant to current treatments; its lead product candidate, VAL-083, is a first-in-class small-molecule DNA-targeting chemotherapeutic agent that induces DNA double-strand breaks and cancer cell death, with clinical activity demonstrated against glioblastoma multiforme (GBM), ovarian cancer, pediatric central nervous system tumors, and other solid tumors including non-small cell lung cancer and head and neck cancers; VAL-083 has completed preclinical, Phase 1, and Phase 2 trials, including for bevacizumab-refractory and MGMT-unmethylated GBM, and is advancing in biomarker-driven Phase 2 trials such as single-agent recurrent TMZ-resistant GBM at MD Anderson Cancer Center and combination with radiation therapy for newly diagnosed MGMT-unmethylated GBM at Sun Yat-sen University. Founded in 2010 and headquartered in Vancouver, British Columbia, Canada, with research and clinical operations in Menlo Park, California, the company collaborates with global academic and clinical institutions including the National Cancer Institute, Global Coalition for Adaptive Research on the GBM AGILE platform trial, and strategic partners in China for commercial rights to VAL-083 in chronic myelogenous leukemia and lung cancer. In 2020, DelMar merged with Adgero Biopharmaceuticals Holdings, Inc., rebranded as Kintara Therapeutics, Inc. (Nasdaq: KTRA), and raised approximately $19.6 million in a private placement to fund VAL-083 and REM-001 photodynamic therapy development for cutaneous metastatic breast cancer; in 2023, Kintara secured a $2 million NIH grant to reinitiate the REM-001 Phase 3-ready program, treating four patients at Memorial Sloan Kettering by late 2024, while pursuing a merger with TuHURA Biosciences, Inc.