CANbridge Pharmaceuticals Inc.

CANbridge Pharmaceuticals Inc.

HHKEX:1228
1.85
HKD
+0.02
(+1.09%)
56.50MMarket Cap
Apr 01Next Earn
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
0.03
0.33
0.19
0.24
0.2
0.11
- -
Basic EPS, GAAP
-0.51
-1.99
-11.43
-1.14
-0.89
-1.04
0.03
- -
Free Cash Flow per Basic Share
-0.4
-0.72
-6.29
-0.74
-0.75
-0.29
-0.08
- -
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-2.34
-4.12
1.63
0.73
-0.09
-1.12
-0.67
-1.12
Tangible Book Value per Share
-2.43
-4.54
1.51
0.57
-0.27
-1.28
-0.78
-1.28
Basic Weighted Avg Shares
424
424
94
424
424
425
454
425
Sales/Revenue/Turnover
1
12
31
79
103
85
50
- -
Operating Margin (%)
-9,315.52
-1,920.65
-2,101.16
-569.21
-354.92
-399.29
-183.19
- -
Depreciation Expense
4
18
16
22
28
27
12
- -
Net Income, GAAP
-218
-846
-1,077
-483
-379
-443
15
- -
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
-14,817.9
-7,031.61
-3,456.26
-612.21
-368.26
-520.1
29.65
- -
Working Capital
-6
283
626
227
-118
-437
-345
-437
LT Debt
58
19
13
115
107
109
8
109
Total Equity
-991
-1,746
693
309
-40
-474
-342
-474
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
-5.13
- -
Return on Common Equity (%)
- -
- -
- -
-96.51
- -
- -
- -
- -

Capital Structure

CNY

•

in mil. unless spec.
Dec'23
Jun'24
Dec'24
ST Debt
35
42
27
LT Borrowings
7
16
15
LT Finance Leases
101
96
94
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
425
425
425
Market Capitalization
382
130
53

Working Capital

CNY

•

in mil. unless spec.
Dec'23
Jun'24
Dec'24
Total Current Assets
210
102
45
Cash, Cash Equivalents & STI
125
43
10
Accounts Receivable, Net
31
28
17
Inventories
9
13
8
Total Current Liabilities
328
417
483
Payables & Accruals
- -
- -
- -
ST Debt
35
42
27
Deferred Revenue
- -
- -
- -

Growth Rates

CNY

•

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
151.29%
-27.97%
Free Cash Flow
- -
-16.38%
-68.8%
Net Income, GAAP
- -
-27.19%
-103.35%
Sales/Revenue/Turnover
- -
56.83%
-41.27%
Total Cash Common Dividend
- -
- -
- -

Semi-annual Revenue

CNY

•

in mil. unless spec.

Year

H1
H2
FY
2023
- -
- -
103
2024
- -
- -
85
2025
- -
- -
50

Semi-annual Earnings Per Share

CNY

•

in mil. unless spec.

Year

H1
H2
FY
2023
- -
- -
-0.89
2024
- -
- -
-1.04
2025
- -
- -
0.03

Semi-annual Dividends Per Share

CNY

•

in mil. unless spec.

Year

H1
H2
FY
2023
- -
- -
- -
2024
- -
- -
- -
2025
- -
- -
- -

Company Description

CEO
Qun Xue
Full Time Employees
41
Sector
Health technology
Industry
Pharmaceuticals: major
Address
Suzhou Industrial Park, Building 21 Beijing BE China
IPO Date
Dec 10, 2021
Business
CANbridge Pharmaceuticals Inc. (HKEX:1228) is a global biopharmaceutical company focused on the research, development and commercialization of transformative therapies for rare diseases, with a foundation in China. Established in 2012 and headquartered in Suzhou, China, the company offers approved products including Hunterase (idursulfase beta), an enzyme replacement therapy for Mucopolysaccharidosis type II (Hunter syndrome); Livmarli (maralixibat oral solution), an ileal bile acid transporter inhibitor for cholestatic pruritus in Alagille syndrome and progressive familial intrahepatic cholestasis; and Gaurunning (velaglucerase beta for injection), an enzyme replacement therapy for Type 1 and Type 3 Gaucher disease. Its pipeline comprises seven assets such as CAN106 (omoprubart), a long-acting monoclonal antibody for complement-mediated disorders including paroxysmal nocturnal hemoglobinuria; gene therapies for Pompe disease, Fabry disease and Duchenne muscular dystrophy developed at its Next-Generation Innovation Facility; and treatments targeting hemophilia A, metabolic disorders and neuromuscular diseases. CANbridge operates across mainland China, Hong Kong, Macau, Taiwan, the United States and collaborates globally with partners including Apogenix, GC Pharma, Mirum Pharmaceuticals, WuXi Biologics, Privus, UMass Chan Medical School, University of Washington School of Medicine and Scriptr Global. In August 2025, CANbridge entered a strategic partnership with Qingdao Baheal Medical Inc., securing approximately HK$100 million in equity investment and designating a Baheal subsidiary as exclusive commercial services organization for select products in mainland China, Hong Kong and Macau to enhance commercialization capabilities; the company also received NMPA marketing approval for Gaurunning in May 2025 via priority review, accepted NDAs for expanded Livmarli indications and advanced CAN106 and gene therapy programs with positive clinical data.

Company News

  • CANbridge to Continue CAN008 Phase 2 Trial in Glioblastoma Multiforme (GBM) in China Based on Interim Analysis of Independent Data Monitoring Committee

  • CANbridge Reports Positive Preliminary Data in the Omoprubart (CAN106) Phase 1b Trial in Paroxysmal Nocturnal Hemoglobinuria (PNH) in China

  • CANbridge Announces Marketing Approval of CAN108 (迈芮倍®/LIVMARLI®) in China for the Treatment of Cholestatic Pruritus in Patients with Alagille Syndrome

  • CANbridge Pharmaceuticals Appoints Jason West Vice President, Head of Gene Therapy Research

  • CANbridge Pharmaceuticals CAN008 Phase 2 Trial for Treatment of Glioblastoma Multiforme (GBM) in China Reaches Full Enrollment

  • Long-Term Data from CANbridge Pharmaceuticals CAN008 Phase 1/2 Trial in Glioblastoma Multiforme Shows 67% Five-Year Overall Survival Rate Compared to 8.2% in Institutional Database