Lepu Biopharma Co. Ltd. Class H

Lepu Biopharma Co. Ltd. Class H

HHKEX:2157
3.75
HKD
-0.43
(-10.29%)
8.97BMarket Cap
Mar 31Next Earn
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
- -
0.01
0.14
0.22
0.53
- -
Basic EPS, GAAP
-0.27
-0.35
-0.61
-0.42
-0.01
-0.24
0.15
- -
Free Cash Flow per Basic Share
-0.36
-0.44
-0.51
-0.36
-0.18
-0.15
-0.07
- -
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-0.21
0.89
0.5
0.54
0.54
0.41
0.77
0.77
Tangible Book Value per Share
-0.57
0.52
0.15
0.21
0.22
0.1
0.44
0.44
Basic Weighted Avg Shares
1,659
1,659
1,659
1,641
1,659
1,690
1,755
1,737
Sales/Revenue/Turnover
- -
- -
- -
16
225
368
935
- -
Operating Margin (%)
- -
- -
- -
-4,123.91
-170.55
-101.93
10.15
- -
Depreciation Expense
49
84
95
95
103
100
94
- -
Net Income, GAAP
-447
-582
-1,011
-689
-22
-411
261
- -
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
0.67
- -
Profit Margin (%)
- -
- -
- -
-4,424.94
-9.81
-111.85
27.96
- -
Working Capital
-994
461
-235
-31
-222
-398
-20
-20
LT Debt
167
181
252
293
284
267
276
276
Total Equity
-186
1,502
847
901
889
682
1,363
1,363
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
14.23
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
14.74
- -
Return on Common Equity (%)
- -
- -
-87.52
-79.32
-2.46
-51.43
25.02
- -

Capital Structure

CNY

•

in mil. unless spec.
Dec'24
Jun'25
Dec'25
ST Debt
583
674
788
LT Borrowings
256
240
276
LT Finance Leases
11
4
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
1,711
1,711
1,804
Market Capitalization
4,211
8,430
8,058

Working Capital

CNY

•

in mil. unless spec.
Dec'24
Jun'25
Dec'25
Total Current Assets
646
704
1,142
Cash, Cash Equivalents & STI
465
536
959
Accounts Receivable, Net
46
50
67
Inventories
23
47
52
Total Current Liabilities
1,044
1,112
1,162
Payables & Accruals
- -
- -
- -
ST Debt
583
674
788
Deferred Revenue
- -
- -
- -

Growth Rates

CNY

•

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
7.6%
99.88%
Free Cash Flow
- -
-25.24%
-49.1%
Net Income, GAAP
- -
308.67%
-163.53%
Sales/Revenue/Turnover
- -
- -
154.18%
Total Cash Common Dividend
- -
- -
- -

Semi-annual Revenue

CNY

•

in mil. unless spec.

Year

H1
H2
FY
2023
- -
- -
225
2024
- -
- -
368
2025
- -
- -
935

Semi-annual Earnings Per Share

CNY

•

in mil. unless spec.

Year

H1
H2
FY
2023
- -
- -
-0.01
2024
- -
- -
-0.24
2025
- -
- -
0.15

Semi-annual Dividends Per Share

CNY

•

in mil. unless spec.

Year

H1
H2
FY
2023
- -
- -
- -
2024
- -
- -
- -
2025
- -
- -
- -

Company Description

CEO
Ziye Sui
Full Time Employees
710
Sector
Health technology
Industry
Pharmaceuticals: major
Address
Block 4 Shanghai SH China 201612
IPO Date
Feb 23, 2022
Business
Lepu Biopharma Co., Ltd. (2157.HK) is a China-based biopharmaceutical company focused on the discovery, development, and commercialization of oncology therapeutics, including antibody-drug conjugates (ADCs), oncolytic virus drugs, and immunotherapies. Founded in 2018 and headquartered in Shanghai, the company operates primarily in China with a global vision, advancing pipelines through clinical and pre-clinical stages for tumor treatments targeting unmet medical needs in cancer patients. Its core products and services encompass two commercial-stage products; eight clinical-stage candidates, six of which are ADCs such as MRG003 (EGFR-targeted), MRG002 (HER2-targeted), MRG004A (TF-targeted), and CMG901 (CLDN18.2-targeted); oncolytic virus therapies like LP002; immunotherapies including HX008; and three clinical-stage combination therapies, supported by an integrated ADC technology platform covering drug discovery, clinical development, CMC, and GMP-compliant manufacturing. The company serves domestic and international markets, with products sold at home and abroad, and maintains key pipeline assets like MRG003, MRG002, HX008, and LP002 in advanced development. In recent developments, Lepu Biopharma entered into an exclusive global licensing agreement with ArriVent BioPharma in January 2025 for ARR-217 (MRG007), an ADC targeting gastrointestinal cancers, granting ArriVent rights outside Greater China. It also partnered with BioDlink and Chime Biologics for commercial production advancements, including the world's first EGFR-targeted ADC launch, and licensed CMG901 to AstraZeneca via joint venture KYM in 2023, recognizing milestone payments in 2024; additionally, in 2025, it completed a licensing transaction and Series A fundraising for Excalipoint Cayman to globalize pipelines while prioritizing next-generation ADCs and IO bi/tri-specific antibodies.