Transcenta Holding Limited (6628.HK) is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of antibody-based and antibody-drug conjugate therapeutics targeting difficult-to-treat solid tumors. The company offers a pipeline of product candidates including TST001, a PD-L1 x VEGF bispecific antibody; TST002, a Claudin18.2 antibody-drug conjugate; TST003, an anti-TL1A antibody; and others such as TST004 (EGFR antibody), TST005 (ROR1 antibody), and TST009 (DR5 x TLR9 bispecific antibody), primarily through its proprietary Transcenta Antibody Discovery System (TADS) platform and Hua Medicine diabetes pipeline assets. Transcenta operates in the oncology and metabolic disease segments, targeting unmet needs in solid tumors and type 2 diabetes with customers including pharmaceutical partners and clinical trial participants across Asia, North America, and Europe; it was founded in 2018 and is headquartered in Suzhou, China, with additional facilities in Hefei, China, and Rockville, Maryland, USA. Recently, in 2024, Transcenta completed a strategic business combination with Cartesian Therapeutics, adopting the new name Cartesian Therapeutics, Inc. (NASDAQ: RNAC), which expanded its pipeline into autoimmune diseases while retaining its oncology focus; this followed the delisting from the Hong Kong Stock Exchange and marked a major reorganization including leadership transitions and integration of Hua Medicine's diabetes assets. The company also advanced multiple clinical trials, such as Phase II for TST001 in gastric cancer and partnerships for global development rights.