IDEAYA Biosciences, Inc.
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- IDEAYA Biosciences, Inc. is a clinical-stage precision medicine oncology company focused on the discovery, development, and commercialization of targeted therapeutics principally in precision oncology. The company’s core product pipeline includes small-molecule drugs and antibody-drug conjugates (ADCs) centered around synthetic lethality and biomarkers-driven patient selection. Key products in clinical development include darovasertib (IDE196), a protein kinase C (PKC) inhibitor for tumors with GNAQ or GNA11 mutations such as uveal melanoma; IDE397, a methionine adenosyltransferase 2A (MAT2A) inhibitor targeting cancers with MTAP gene deletions; IDE161, a poly(ADP-ribose) glycohydrolase (PARG) inhibitor for tumors with homologous recombination deficiency (HRD); and IDE034, a bispecific B7H3/PTK7 TOP1 antibody-drug conjugate designed for solid tumors expressing these targets. IDEAYA employs integrated biomarker and small molecule drug discovery platforms and collaborates with leading pharmaceutical companies to advance its pipeline globally. The company operates primarily out of South San Francisco, California, and was founded to leverage synthetic lethality approaches to selectively target cancer vulnerabilities while sparing normal cells. Recent major corporate developments include strategic partnerships and collaborations with pharmaceutical companies such as GlaxoSmithKline (GSK), which focuses on IDEAYA’s synthetic lethality programs including MAT2A, Pol Theta, and Werner Helicase, with shared development costs and profit-sharing arrangements. Partnership with Gilead centers on the IDE397 program, and a collaboration with Pfizer supports development of darovasertib. Additionally, in September 2025, IDEAYA entered a global licensing and collaboration agreement with Servier, under which Servier obtained rights to darovasertib outside the U.S., bringing in $210 million upfront plus up to $320 million in milestones, expanding the commercial and clinical development reach of this program worldwide. In December 2025, the U.S. Food and Drug Administration cleared IDEAYA’s investigational new drug application for IDE034, initiating a Phase 1 clinical trial enrolling patients in the first quarter of 2026 targeting multiple solid tumors including lung, colorectal, head and neck, and ovarian cancers. These recent advances underscore IDEAYA’s commitment to advancing potentially first-in-class, precision-guided oncology therapies and expanding its clinical pipeline while strategically leveraging partnerships to enhance global development and commercialization efforts.
Company News
IDEAYA Biosciences and Servier Announce Data From Three Clinical Trials at ESMO 2026 Supporting the Potential of Darovasertib to Become a Foundational New Therapy for Patients Across the Treatment Journey of Uveal Melanoma
IDEAYA Biosciences (NASDAQ:IDYA) CEO Sells $985,304.58 in Stock
IDEAYA Biosciences (NASDAQ:IDYA) Stock Jumps 4.8% – Here’s What Happened
IDEAYA Biosciences Announces the Promotion of Dr. Michael White to President, Research and Development
IDEAYA Biosciences Announces Inducement Grants under Nasdaq Listing Rule 5635(c)(4)
Squarepoint Ops LLC Has $940,000 Holdings in IDEAYA Biosciences, Inc. $IDYA
IDEAYA Biosciences, Inc. (IDYA) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript
IDEAYA Biosciences and Servier Announce First Patient Dosed in OptimUM-11 Global Phase 3 Registrational Trial of Darovasertib and Crizotinib as Adjuvant Therapy for Subjects with Uveal Melanoma
IDEAYA Biosciences Announces London Investor R&D Day and Participation in Upcoming September 2026 Investor Conferences
IDEAYA Biosciences Announces Successful FDA Type C Meeting for IDE849, DLL3 TOP1 ADC, on Phase 3 Registrational Trial Design for Potential Accelerated and Full Approval in Extensive Stage Small Cell Lung Cancer
IDEAYA Biosciences Announces Inducement Grants under Nasdaq Listing Rule 5635(c)(4)
IDEAYA Biosciences Announces Inducement Grants under Nasdaq Listing Rule 5635(c)(4)
Ideaya Biosciences: Darovasertib De-Risks A Self-Reinforcing Oncology Platform
IDEAYA Biosciences Announces Clinical Collaboration with Genentech in MTAP-Deleted KRAS G12D-Mutant Pancreatic Cancer
IDEAYA Biosciences Reports Second Quarter 2026 Financial Results and Provides Business Update
IDEAYA Biosciences Announces Inducement Grants under Nasdaq Listing Rule 5635(c)(4)
IDEAYA Biosciences Announces IDE892, a Potential Best-in-Class MTA-Cooperative PRMT5 Inhibitor, Initiates Part 2 Monotherapy Expansion in the Phase 1/2 Study in MTAP-Deleted Pancreatic and Lung Cancers
IDEAYA Biosciences Announces ESMO 2026 Presentations for Darovasertib and IDE849 Clinical Programs
IDEAYA Biosciences Announces Inducement Grants under Nasdaq Listing Rule 5635(c)(4)
IDEAYA Biosciences Announces Yujiro S. Hata Elected Chairman of its Board of Directors