Immunic, Inc.
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- Immunic, Inc. (Nasdaq: IMUX) develops a clinical-stage pipeline of orally administered small molecule therapies targeting chronic inflammatory and autoimmune diseases, including multiple sclerosis and gastrointestinal disorders; its lead product candidate, vidofludimus calcium (IMU-838), advances in phase 3 ENSURE trials for relapsing multiple sclerosis and phase 2 CALLIPER trial for progressive multiple sclerosis, demonstrating neuroprotective effects via nuclear receptor related 1 (Nurr1) activation alongside anti-inflammatory and antiviral activity through dihydroorotate dehydrogenase (DHODH) inhibition; IMU-856, a Sirtuin 6 (SIRT6) modulator, prepares for phase 2 trials in celiac disease and other gastrointestinal conditions such as inflammatory bowel disease and graft-versus-host disease; IMU-935 (izumerogant), an IL-17/RORγt inverse agonist, targets psoriasis and castration-resistant prostate cancer; and IMU-381 enters preclinical development for gastrointestinal diseases. The company, founded in 2016 as Immunic AG in Planegg-Martinsried, Germany, reorganized in April 2019 as Immunic, Inc., a Delaware corporation headquartered in New York City with its subsidiary Immunic AG in Gräfelfing near Munich conducting research and development activities; it operates primarily in the United States and Germany, serving patients with high unmet needs in neurology and gastroenterology. Recent developments include completion of enrollment in both phase 3 ENSURE trials for vidofludimus calcium in June 2025 with top-line data expected by end-2026; positive phase 2 CALLIPER results in April 2025 showing 23.8% reduction in 24-week confirmed disability worsening in progressive multiple sclerosis; long-term open-label extension data from phase 2 EMPhASIS trial in June 2025 with over 92% of relapsing-remitting multiple sclerosis patients free of disability worsening at week 144; a $65 million oversubscribed public offering in May 2025 co-led by BVF Partners and Coastlands Capital; and a $5.1 million registered direct offering led by Aberdeen Investments in April 2025.
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Immunic presents new vidofludimus calcium data at multiple sclerosis conference
Immunic to Present Additional Phase 2 CALLIPER Trial Data for Vidofludimus Calcium at the CMSC Annual Meeting 2026, Reinforcing Its Potential in Progressive Multiple Sclerosis
Immunic presents new vidofludimus calcium data at multiple sclerosis conference
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Immunic names Erik Lundgren as CEO as it advances Phase 3 MS trials
Immunic Appoints Distinguished Biopharmaceutical Executive Erik Lundgren as Chief Executive Officer
Immunic names Erik Lundgren as CEO as it advances Phase 3 MS trials
EXCLUSIVE: Immunic Appoints Former Genentech Exec Erik Lundgren As CEO
Immunic appoints Biogen, Cubist veteran Mike Bonney as board chair ahead of key MS trial readout
Immunic Appoints Seasoned Biopharmaceutical Executive Michael W. Bonney as Chair of the Board of Directors
Immunic advances Phase 3 MS program, eyes topline data by year-end
Immunic, Inc. Reports First Quarter 2026 Financial Results and Provides Corporate Update
Immunic advances Phase 3 MS program, eyes topline data by year-end
Immunic: Saved By A 200 Million Private Placement
Immunic to Participate in Investor and Medical Conferences in May
Immunic appoints Michael Panzara as CMO ahead of pivotal MS drug readout
Immunic Appoints Accomplished Biopharmaceutical Executive Michael A. Panzara, M.D.
Immunic to implement 1-for-10 reverse stock split