- CEO
- Vishal Mehta
- Full Time Employees
- 30
- Sector
- Healthcare
- Industry
- Medical - Pharmaceuticals
- Address
- 1100 Massachusetts Avenue Cambridge MA United States of America 02138
- IPO Date
- Jul 27, 2000
- Business
- Infinity Pharmaceuticals, Inc. (INFIQ) is a clinical-stage biopharmaceutical company focused on developing small-molecule drugs targeting oncology pathways, including PI3K inhibitors for immuno-oncology applications; eganelisib (IPI-549), a selective PI3K-gamma inhibitor designed to reprogram immunosuppressive macrophages in the tumor microenvironment for solid tumors such as triple-negative breast cancer, urothelial cancer, and renal cell carcinoma; duvelisib, a dual PI3K-delta/gamma inhibitor previously advanced for hematologic malignancies like chronic lymphocytic leukemia; and earlier candidates including IPI-3063 (PI3K-delta), IPI-443 (PI3K-delta/gamma), IPI-493 (HSP90B), and IPI-926 (Hedgehog pathway). The company, founded in 1995 and headquartered in Cambridge, Massachusetts, has conducted operations primarily in the United States with global clinical trials through partnerships; it previously collaborated with Bristol-Myers Squibb on MARIO trials combining eganelisib with Opdivo, Roche/Genentech on front-line combinations with Tecentriq and Avastin/Abraxane, Arcus Biosciences on adenosine receptor antagonist regimens, and PellePharm on patidegib licensing. In recent major changes, Infinity filed for Chapter 11 bankruptcy on September 29, 2023, following the termination of a proposed merger with MEI Pharma due to activist shareholder opposition, leading to significant workforce reductions of approximately 75-78%; the U.S. Bankruptcy Court approved asset sales, including certain assets to Deerfield Healthcare Innovations Fund III for $1 million in December 2023 and substantially all remaining assets to an undisclosed healthcare investment firm in February 2024, with a revised liquidation plan confirmed on March 7, 2024, to distribute proceeds to creditors amid $21 million in assets and $58.6 million in liabilities.