Opus Genetics, Inc.

Opus Genetics, Inc.

IRD
Opus Genetics, Inc.US flagNASDAQ Global Market
4.20
USD
+0.21
- -
341.86MMarket Cap
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
0.04
2
0.88
0.41
0.23
0.16
Basic EPS, GAAP
-0.87
-5.28
-3.82
0.9
-0.46
-2.15
-0.8
-1.45
Free Cash Flow per Basic Share
-0.51
-1.46
-1.3
0.72
-0.05
-0.96
-0.57
-0.53
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-1.14
-7.01
-6.02
-3.59
-3.77
-5.2
-3.03
-3.45
Tangible Book Value per Share
-1.07
-2.89
1.5
2.32
2.31
0.25
0.25
-0.62
Basic Weighted Avg Shares
7
5
15
20
22
27
62
74
Sales/Revenue/Turnover
- -
- -
1
40
19
11
14
12
Operating Margin (%)
- -
- -
-3,854.84
45.74
-55.45
-309.99
-271.9
-359.13
Depreciation Expense
- -
- -
- -
- -
- -
- -
- -
- -
Net Income, GAAP
-6
-25
-57
18
-10
-58
-50
-107
Effective Tax Rate (%)
- -
- -
- -
1.73
- -
- -
- -
- -
Profit Margin (%)
- -
- -
-9,625.3
44.89
-52.42
-523.4
-349.33
-892.36
Working Capital
-8
14
22
46
50
25
42
57
LT Debt
- -
- -
- -
- -
- -
- -
1
1
Total Equity
-8
-13
22
46
50
7
15
-46
Return on Invested Capital (%)
- -
- -
- -
51.68
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
-22.33
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
- -
- -
- -
LT Borrowings
1
1
1
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
65
70
71
Market Capitalization
92
112
335

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
36
50
67
Cash, Cash Equivalents & STI
31
45
60
Accounts Receivable, Net
3
2
2
Inventories
- -
- -
- -
Total Current Liabilities
29
8
9
Payables & Accruals
6
8
9
ST Debt
- -
- -
- -
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
-21.45%
128.26%
Free Cash Flow
- -
428.23%
37.84%
Net Income, GAAP
- -
61.04%
-13.8%
Sales/Revenue/Turnover
- -
- -
29.15%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
2
1
4
4
11
2025
4
3
3
4
14
2026
2
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.29
-0.3
-0.29
- -
-2.15
2025
-0.24
-0.12
-0.25
- -
-0.8
2026
-0.75
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
George Magrath
Full Time Employees
18
Sector
Healthcare
Industry
Biotechnology
Address
37000 Grand River Avenue Durham MI United States of America 48335
IPO Date
Jan 19, 2015
Business
Opus Genetics, Inc. is a leading clinical-stage biopharmaceutical firm dedicated to pioneering advanced therapeutic solutions for patients grappling with inherited retinal diseases and various other ophthalmic conditions. The company’s robust pipeline prominently features adeno-associated virus (AAV)-based gene therapies, including its primary candidate, OPGx-LCA5, which has demonstrated promising early visual improvements in a Phase 1/2 clinical trial for Leber congenital amaurosis type 5 and is progressing towards a pivotal adaptive Phase 3 study. Another key gene therapy, OPGx-BEST1, designed for BEST1-related inherited retinal disease, recently commenced its Phase 1/2 clinical trial. Beyond gene therapies, Opus Genetics also offers Phentolamine Ophthalmic Solution, already approved for reversing pharmacologically induced mydriasis, and is evaluating it in late-stage Phase 3 trials for presbyopia and impaired dim light vision following keratorefractive surgery. Formerly operating as Ocuphire Pharma, Inc., the entity transformed into Opus Genetics, Inc. in October 2024 through an all-stock acquisition, signifying a strategic pivot towards gene therapy development. The company continues to advance a diverse portfolio from its headquarters in Research Triangle Park, North Carolina.

Company News

APIChat
  • Opus Genetics to Host Virtual R&D Science Forum on Tuesday, June 16, 2026 Featuring Multiple Inherited Retinal Disease Experts

  • Opus Genetics to Host Virtual R&D Science Forum on Tuesday, June 16, 2026 Featuring Multiple Inherited Retinal Disease Experts

  • Opus Genetics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

  • Opus Genetics to Present at the 2026 Jefferies Global Healthcare Conference

  • Opus Genetics Touts Retinal Gene Therapy Pipeline, September BEST1 Data Catalyst

  • Opus Genetics to Present at the RBC Capital Markets 2026 Global Healthcare Conference

  • Opus Genetics, Inc. (IRD) Reports Q1 Loss, Misses Revenue Estimates

  • Opus Genetics Announces Financial Results for First Quarter 2026 and Provides Corporate Update

  • Opus Genetics Presents Clinical and Preclinical Data at ARVO 2026 Demonstrating Continued Pipeline Advancement in Inherited Retinal Diseases

  • Opus Genetics Completes Enrollment in Cohort 1 of Phase 1/2 OPGx-BEST1 Gene Therapy Study

  • Opus Genetics Announces FDA Acceptance of OPGx-LCA5 into Rare Disease Evidence Principles (RDEP) Program

  • Opus Genetics to Participate in Leading Medical Conferences in May 2026

  • Opus Genetics Announces Data Presentations at the 2026 American Society of Cataract and Refractive Surgery Annual Meeting

  • Opus Genetics Solidifies Leadership Position in Gene Therapy Development for Inherited Retinal Diseases with Strategic Long-Term Financing by Oberland Capital

  • Opus Genetics Named to Fast Company's Annual List of the World's Most Innovative Companies of 2026

  • Opus Genetics, Inc. (IRD) Reports Q4 Loss, Tops Revenue Estimates

  • Opus Genetics Announces Financial Results for Full Year 2025 and Provides Corporate Update

  • Opus Genetics to Present at Upcoming Investor Conferences in March 2026

  • Opus Genetics Announces Initial Clinical Data from Phase 1/2 OPGx-BEST1 Gene Therapy Study at the Macula Society Annual Meeting

  • Opus Genetics Announces FDA Acceptance of Supplemental New Drug Application for Phentolamine Ophthalmic Solution 0.75% for the Treatment of Presbyopia