- CEO
- Jeetinder Singh Mahal
- Full Time Employees
- 64
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- 2200 Bridge Pkwy Redwood City DE United States of America 94065
- IPO Date
- Jan 10, 2020
- Business
- Jasper Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing briquilimab, a targeted aglycosylated monoclonal antibody that blocks stem cell factor from binding to the KIT (CD117) receptor on mast cells and hematopoietic stem cells to treat chronic mast cell-driven diseases including chronic spontaneous urticaria (CSU), chronic inducible urticaria (CIndU), and allergic asthma, as well as enabling safer conditioning for stem cell transplantation in hematologic malignancies such as sickle cell disease, Fanconi anemia, and severe combined immunodeficiency. The company, founded in 2018 and headquartered at 2200 Bridge Parkway, Suite 102, Redwood City, California, United States, conducts clinical trials including the ongoing Phase 1b/2a BEACON study in CSU showing promising efficacy with deep and durable responses in multiple dosing cohorts, the SPOTLIGHT study in CIndU, the ETESIAN study in asthma, and open-label extensions, while also advancing briquilimab in stem cell transplant conditioning regimens demonstrated in prior studies to support engraftment without typical toxicities. Recent developments include promising July 2025 BEACON data updates despite isolated drug lot investigations concluded not related to manufacturing with final key opinion leader-reviewed results expected in Q4 2025, continued patient enrollment toward Phase 2b CSU dose selection and study start mid-2026 with additional data in early Q1 2026, a $30 million underwritten public offering of common stock and warrants completed in Q3 2025 extending cash runway through Q1 2026 alongside $50.9 million cash on hand as of September 30, 2025, and a prior $45 million private placement in October 2024.