- Sector
- Healthcare
- Industry
- Biotechnology
- Address
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- IPO Date
- Jul 28, 2000
- Business
- Keryx Biopharmaceuticals, Inc. is a biopharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of renal disease. Its core products include Auryxia (ferric citrate), an FDA-approved oral absorbable iron-based compound used to control serum phosphorus levels in patients with chronic kidney disease (CKD) on dialysis and to treat iron deficiency anemia in adults with CKD not on dialysis. Auryxia is also marketed in Japan under the brand name Riona through strategic partnerships with Japan Tobacco Inc. and Torii Pharmaceutical Co. Ltd. The company operates globally with commercial and operational presence in the United States, including offices in Boston and New York, and has additional operations in the UK and Israel. Founded in 1997 and headquartered in Boston, Massachusetts, Keryx's product portfolio targets kidney disease patients with a focus on managing hyperphosphatemia and related complications.
In recent years, Keryx underwent a significant strategic change through its merger with Akebia Therapeutics in 2018, forming an expanded entity with a complementary nephrology portfolio, including the late-stage HIF-PHI candidate vadadustat for anemia treatment in CKD. Following the merger, Keryx continues to operate as a wholly-owned subsidiary of Akebia Therapeutics. The company has also engaged in manufacturing and supply agreements, such as its master manufacturing services agreement with Siegfried. Recent developments include regulatory submissions and clinical trials focused on expanding the indications for ferric citrate, enhancing treatment options for non-dialysis dependent CKD patients. Keryx maintains strategic alliances in Japan and with partners for development and marketing in other regions to broaden its market reach and support commercialization efforts.