ToolGen Incorporated ToolGen Incorporated (199800.KQ), a biotechnology company founded in 1999 and headquartered in Seoul, South Korea, develops advanced genome editing technologies, including clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 gene scissors, ribose nucleic acid (RNA)-guided endonucleases (RGEN), and deoxyribonucleic acid (DNA)-directed RGEN (dRGEN) for precise editing of genetic information in microbial, plant, animal, and human cells; it also provides genome engineering services, patent licensing and monetization, therapeutics for genetic and rare diseases, and seed businesses focused on high-value crops such as stress-tolerant, pest-resistant soybeans using CRISPR-Cas9 technology. The company operates primarily in South Korea with approximately 80 employees and targets biomedicine, agriculture, and research sectors through strategic collaborations with academia and industry partners. Recent developments include a strategic cross-license agreement with GenEditBio Limited in November 2025 to combine ToolGen's CRISPR-Cas9 platform with GenEditBio's lipid nanoparticle delivery systems for in vivo genome-editing therapeutics like GEB-200, following successful proof-of-concept studies in non-human primates; additionally, ToolGen filed a patent infringement lawsuit against Vertex Pharmaceuticals in the United Kingdom in April 2025 over the genome editing therapy CASGEVY.