OliX Pharmaceuticals, Inc. operates as a clinical-stage biotechnology firm, dedicated to advancing RNA interference (RNAi) based therapies for a range of medical conditions. The company leverages its proprietary asymmetric siRNA (asiRNA) and cell-penetrating asymmetric siRNA (cp-asiRNA) platforms, designed to enhance gene silencing with reduced off-target effects and improved cellular delivery. Its diverse investigational portfolio includes compounds addressing various therapeutic areas. Within the dermal segment, lead candidates include OLX101A for hypertrophic scarring, which completed Phase 2a enrollment in the U.S. and has been licensed for development, alongside OLX104C targeting androgenic alopecia. The ophthalmic pipeline features OLX301A for dry and wet age-related macular degeneration (AMD), currently in Phase 1 trials in the U.S., and OLX10212, which received U.S. FDA IND approval for Phase 1 studies in AMD. OLX304A is also under development for retinitis pigmentosa. For pulmonary diseases, compounds like OLX201 are being developed for lung fibrosis. Expanding into systemic treatments, OliX utilizes its GalNAc-asiRNA technology for liver-focused therapies, including OLX75016 for metabolic-associated steatohepatitis (MASH) and other cardiometabolic indications, a program that secured a significant global licensing agreement with Eli Lilly and Company in February 2025. OLX702A for NASH and OLX703A for hepatitis B virus are also in preclinical development. The company has also initiated collaborations for RNA-based antibody-drug conjugate (ADC) therapeutics and entered an exclusive scientific partnership with L'Oréal Groupe for beauty innovation in skin and hair regeneration. Established in 2010, OliX Pharmaceuticals, Inc. is headquartered in Seongnam, South Korea.