MedPacto, Inc. (KOSDAQ: 235980) is a clinical-stage biopharmaceutical company that discovers, develops and commercializes innovative therapeutics targeting cancer and autoimmune diseases using genome-based biomarker approaches. The company offers a pipeline of small molecule drugs and antibodies, including its lead candidate vactosertib, a TGF-β signaling inhibitor indicated for solid tumors such as gastric cancer, pancreatic cancer, colorectal cancer, non-small cell lung cancer, bladder cancer and desmoid tumors; ME-1601mAb targeting BSP1 for various cancers; MS-1601A targeting TRG1 for cancers and autoimmune indications; MA-B2 antibody therapeutics; and additional biomarker-driven candidates for multiple myeloma, triple-negative breast cancer, osteosarcoma and blood cancers. MedPacto conducts operations primarily in South Korea with global clinical development collaborations and maintains U.S. and European regulatory designations including multiple FDA orphan drug approvals. Founded in 2013 and headquartered at 92 Myeongdal-ro, Seocho-gu, Seoul, the company employs approximately 61 people and listed on KOSDAQ in December 2019. In recent developments, MedPacto formed a strategic partnership with Chime Biologics in October 2024 to advance CMC process development and cGMP manufacturing for multiple preclinical candidates targeting IND submissions; completed Phase 1b/2a studies of vactosertib in combination with AstraZeneca's Imfinzi in February 2025 and Merck's Keytruda in June 2024; raised 74.1 billion KRW in capital in December 2023 to support clinical trials; secured U.S. FDA approval for a Phase 2b/3 study of vactosertib plus Keytruda in December 2023; and entered a business agreement with AI-based drug developer Hits in February 2022.