- CEO
- Geordan G. Pursglove
- Full Time Employees
- 2
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- 680 East Colorado Boulevard Pasadena CA United States of America 91101
- IPO Date
- Nov 27, 2020
- Business
- Lixte Biotechnology Holdings, Inc. (Nasdaq: LIXT, LIXTW) is a clinical-stage pharmaceutical company that develops protein phosphatase 2A (PP2A) inhibitors for oncology treatments; its lead product candidate, LB-100, enhances the efficacy of chemotherapy and immunotherapy by promoting neoantigen production, cytokine release, T-cell proliferation, and disruption of cancer cell DNA repair mechanisms; LB-100 advances in phase 1b/2 clinical trials for ovarian clear cell carcinoma combined with dostarlimab, microsatellite stable metastatic colon cancer combined with atezolizumab, and advanced soft tissue sarcoma with standard chemotherapy. The company, founded in 2005 and headquartered in Pasadena, California, targets solid tumors with unmet needs through its proprietary, patented platform with no known direct competitors. Recent developments include the November 2025 acquisition of Liora Technologies' proprietary LiGHT System proton therapy platform, establishing Liora as a wholly owned subsidiary to enter the radiotherapy segment and pursue scalable high-precision cancer treatments; a September 2025 strategic purchase of 10.5 Bitcoin and 300 Ethereum for $2.6 million to diversify treasury holdings up to 50%; two financings raising $6.5 million and Nasdaq compliance regain in August 2025; appointment of two new board members and relocation of corporate headquarters to Boca Raton, Florida, in September 2025; and confirmation of advanced acquisition negotiations for complementary oncology assets.