Lantern Pharma Inc.
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- Business
- Lantern Pharma Inc. (Nasdaq: LTRN) is a clinical-stage biopharmaceutical company that leverages artificial intelligence, machine learning, and genomics through its proprietary RADR platform—incorporating over 200 billion oncology-focused data points—to accelerate precision oncology drug development, rescue failed candidates, and identify responsive patient populations via biomarker-driven approaches; the platform supports drug positioning, combination strategies, and companion diagnostics across solid tumors and blood cancers. Founded in 2013 and headquartered in Dallas, Texas, the company advances a pipeline including LP-300 in Phase 2 trials for non-small cell lung cancer (NSCLC) adenocarcinoma in never-smokers via the Harmonic trial; LP-184 in Phase 1 for solid tumors such as triple-negative breast cancer (TNBC), NSCLC, bladder cancer, pancreatic cancer, glioblastoma, and other central nervous system (CNS) cancers; LP-284 in Phase 1 for non-Hodgkin lymphomas including mantle cell lymphoma and high-grade B-cell lymphoma; and preclinical antibody-drug conjugate (ADC) programs targeting HER2-expressing models with cryptophycin conjugates, alongside STAR-001 through its wholly owned subsidiary Starlight Therapeutics for glioblastoma, brain metastases, atypical teratoid rhabdoid tumors (ATRT), and pediatric CNS cancers with Rare Pediatric Disease Designations. Lantern Pharma operates primarily in the United States with global research collaborations, focusing on genetically defined cancers and limited-treatment indications to reduce development timelines to 2-3 years at $1.0-2.5 million per program versus traditional methods. Recent developments include completion of LP-184 Phase 1a enrollment in September 2025 with a 48% disease control rate in heavily pretreated patients, tumor reductions in DNA damage repair (DDR)-mutated cancers (e.g., CHK2, ATM, BRCA1), and all primary endpoints met; positive FDA Type C meeting outcomes confirming parallel ATRT cohorts, spironolactone combinations, and regulatory paths for Starlight's pediatric CNS program; expansion of LP-284 sites for lymphoma enrollment and preclinical evaluation in autoimmune indications; planned Q1 2026 initiations for pediatric CNS trials, LP-184 Phase 1b/2 in TNBC/NSCLC, and investigator-led bladder cancer trials; plus ongoing partnership discussions for combinations informed by RADR synergies with PARP inhibitors, immunotherapy, and rituximab.
Company News
Lantern Pharma Inc. (LTRN) Q2 2026 Earnings Call Transcript
Lantern Pharma Reports Second Quarter 2026 Financial Results and Provides Business Update
Lantern Pharma to Report Second Quarter 2026 Operating & Financial Results on August 14th, 2026 at 9:00 a.m. ET
Lantern Pharma to Report Second Quarter 2026 Operating & Financial Results on August 14th, 2026 at 9:00 a.m. ET
Lantern Pharma (Nasdaq: LTRN) Establishes Open-Medicine AI as a Separate Company to Commercialize and Expand Its Multi-Agent AI Co-Scientist Platform for the Transformation of Medicine
Lantern Pharma (Nasdaq: LTRN) Establishes Open-Medicine AI as a Separate Company to Commercialize and Expand Its Multi-Agent AI Co-Scientist Platform for the Transformation of Medicine
Lantern Pharma to Advance EMA-Cleared Phase 1b/2 Trial of LP-184 (Zirdafulven) in Biomarker-Selected Advanced Bladder Cancer
Lantern Pharma Receives USPTO Notice of Allowance for Patent Covering Biomarker-Guided Treatment with LP-184 (Zirdafulven) in Multiple Solid Tumor Cancers
Lantern Pharma Launches ZetaOmics™ — an Autonomous, Intelligent “Computational Biologist” That Brings Expert-Grade Bioinformatics, Biostatistics & Reasoning to Every Cancer
Lantern Pharma Reports HARMONIC™ Data Showing LP-300 Progression-Free Survival Benefit Deepens with Treatment Duration in EGFR Exon 21 L858R Lung Cancer
Lantern Pharma Reports HARMONIC™ Data Showing LP-300 Progression-Free Survival Benefit Deepens with Treatment Duration in EGFR Exon 21 L858R Lung Cancer
Lantern Pharma Announces Successful Outcome of FDA Type C Meeting Request for HARMONIC™ Phase 2 Trial of LP-300 in Never-Smokers with NSCLC
Lantern Pharma Announces Successful Outcome of FDA Type C Meeting Request for HARMONIC™ Phase 2 Trial of LP-300 in Never-Smokers with NSCLC
Lantern Pharma Reports First Quarter 2026 Financial Results and Provides Business Updates
Lantern Pharma Inc. Announces Closing of up to $9.25 Million Registered Direct Offering with Existing Holders and a Single Institutional Investor
Lantern Pharma Inc. Announces up to $9.25 Million Registered Direct Offering with Existing Holders and a Single Institutional Investor
Lantern Pharma to Report First Quarter 2026 Operating & Financial Results on May 15th, 2026
Lantern Pharma Unveils Roadmap for withZeta.ai — Industry-First, Multi-Agentic Co-Scientist Featuring Swarm Intelligence and Computational Biology Toolkit with the Launch of ZetaSwarm™ and ZetaOmics™
Lantern Pharma Inc. (LTRN) Discusses Live Demonstration of withZeta.ai AI Platform for Rare Cancer Drug Discovery Transcript
Lantern Pharma Inc. (LTRN) Discusses Live Demonstration of withZeta.ai Platform for AI-Driven Oncology Drug Discovery Transcript