MBX Biosciences, Inc. Common Stock
NASDAQ Global SelectCapital Structure
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in mil. unless spec.Company Description
- CEO
- Steve Hoerter
- Full Time Employees
- 63
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- 11711 N. Meridian Street Carmel IN United States of America 46032
- IPO Date
- Sep 13, 2024
- CIK
- 0001776111
- Website
- mbxbio.com
- Similar Companies
- Business
- MBX Biosciences, Inc. (Nasdaq: MBX), a clinical-stage biopharmaceutical company founded in 2018 and headquartered in Carmel, Indiana, develops novel precision endocrine peptide (PEP) therapies utilizing its proprietary PEP platform to treat endocrine and metabolic disorders including hypoparathyroidism, post-bariatric hypoglycemia, and obesity; its lead product candidate, canvuparatide (MBX 2109), a long-acting parathyroid hormone (PTH) peptide prodrug delivered via once-weekly subcutaneous injection, advances in Phase 2 Avail trial for chronic hypoparathyroidism following positive Phase 1 data showing sustained serum calcium elevation, low peak-to-trough ratios, and good tolerability, with Phase 3 initiation planned for 2026; imapextide (MBX 1416), a long-acting GLP-1 receptor antagonist, progresses in Phase 2 for post-bariatric hypoglycemia after Phase 1 pharmacokinetics supporting weekly dosing; MBX 4291, a potent GLP-1/GIP co-agonist prodrug, enters Phase 1 for obesity targeting once-monthly administration with preclinical weight loss comparable to tirzepatide at lower concentrations, alongside additional preclinical programs in rare and prevalent endocrine diseases. The company operates primarily in the United States with a discovery pipeline leveraging advanced chemical modifications, programmable prodrug technologies, and fatty acylation for optimized potency, selectivity, half-life, and tolerability. Recent developments include its initial public offering and upsized follow-on offering in September 2024 raising over $200 million gross proceeds for a cash position of $391.7 million as of September 30, 2025 funding operations into 2029; positive topline Phase 2 Avail results in Q3 2025; a $63.5 million Series C financing in August 2024; executive appointments such as Chief Medical Officer Salomon Azoulay in June 2024 and Chief Scientific Officer Steven Prestrelski in 2023; FDA IND clearance for MBX 1416 in 2023; and $115 million Series B financing in 2022.
Company News
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MBX Biosciences, Inc. (MBX) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript
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MBX Biosciences Announces First Patient Dosed in Pivotal Phase 3 oPTimize Trial of Once-Weekly Canvuparatide in Adults with Hypoparathyroidism
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MBX Biosciences, Inc. (MBX) Discusses One-Year Data From Phase II Open-Label Extension Study of Once-Weekly Canvuparatide Transcript
MBX Biosciences Highlights Sustained Calcium Control In Rare Disease