Monopar Therapeutics Inc.
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- Monopar Therapeutics Inc. (Nasdaq: MNPR) is a clinical-stage biopharmaceutical company that develops novel radiopharmaceuticals for oncology and treatments for rare genetic disorders such as Wilson Disease; its pipeline features clinical-stage MNPR-101-Zr, a radiodiagnostic imaging agent for advanced solid tumors expressing urokinase plasminogen activator receptor (uPAR), clinical-stage MNPR-101-Lu and late-preclinical MNPR-101-Ac radiotherapeutic agents conjugated to lutetium-177 and actinium-225 respectively for the same oncology indications, and late-stage ALXN1840 (bis-choline tetrathiomolybdate), an investigational oral therapy that has completed Phase 3 trials for Wilson Disease. The company builds its portfolio through in-house development, licensing of late preclinical and clinical-stage assets, and strategic collaborations, targeting patients with aggressive cancers and rare diseases. Founded in 2014 and headquartered in Wilmette, Illinois, Monopar conducts operations primarily in the United States with its team based in the Chicago area. Recent developments include the October 2024 exclusive worldwide license agreement with Alexion, an AstraZeneca Rare Disease unit, for ALXN1840, which provides access to a Phase 3-completed asset for an upfront payment of $4 million in cash plus Monopar stock; an amendment and expansion in June 2024 of its radiopharmaceutical collaboration with NorthStar Medical Radioisotopes, securing long-term non-exclusive supply of actinium-225, intellectual property rights, and shared patent applications to support MNPR-101-Ac; and activation of two novel Phase 1 clinical trials for MNPR-101-Zr and MNPR-101-Lu enrolling patients with advanced solid cancers.
Monopar Presents Phase 2 ALXN1840 Data Demonstrating Liver Disease Stabilization and Neurologic Improvement in Treatment-Experienced Wilson Disease Patients at EASL 2026
Monopar Announces Publication of Phase 2 Study Demonstrating ALXN1840 Significantly Improves Copper Balance in Patients with Wilson Disease
Monopar Therapeutics Reports First Quarter 2026 Financial Results and Provides Business Updates
Monopar Presents Phase 3 Data Showing Greater Neurologic Benefit with ALXN1840 vs SoC in Wilson Disease Patients with Neurologic Symptoms at AAN 2026
Monopar Presents Phase 3 Data Showing Greater Neurologic Benefit with ALXN1840 vs SoC in Wilson Disease Patients with Neurologic Symptoms at AAN 2026
Monopar Reports Fourth Quarter and Full-Year 2025 Financial Results and Provides Business Update
Monopar Therapeutics Inc. $MNPR Shares Acquired by Ally Bridge Group NY LLC
Monopar Expands Leadership Team with Appointment of Seasoned Biopharma Executive Susan Rodriguez as Chief Commercial and Strategy Officer
What Awaits These 4 Biotech Stocks That More Than Doubled in 2025
Monopar Therapeutics (NASDAQ:MNPR) Shares Gap Down After Earnings Miss
Monopar Therapeutics Reports Third Quarter 2025 Financial Results and Recent Developments
Monopar Presents New Data and Analyses on Rapidly Improved Copper Balance in Wilson Disease Patients on Tiomolybdate Choline at AASLD - The Liver Meeting® 2025
Monopar Therapeutics Inc. (NASDAQ:MNPR) Given Average Rating of “Buy” by Analysts
Does Monopar Therapeutics (MNPR) Have the Potential to Rally 42.46% as Wall Street Analysts Expect?
Monopar Announces Abstract Accepted for Oral Presentation at AASLD - The Liver Meeting® 2025
Monopar Therapeutics Inc. Announces Pricing of $135 Million Underwritten Offering of Common Stock and Pre-Funded Warrants
Monopar Announces Journal of Hepatology Publishes Physicians' Letter to the Editor Demonstrating ALXN1840 Rapidly Improved Copper Balance in Wilson Disease Patients
Why Monopar Therapeutics, A Top 1% Biotech Stock, Just Surged Into A Breakout
Monopar Therapeutics: A Speculative Buy On 2 Fronts With Catalysts Imminent
Monopar Announces Abstract Accepted with Distinction for Oral and Poster Presentations at the Upcoming American Neurological Association 2025 Annual Meeting