Ono Pharmaceutical Co., Ltd.

Ono Pharmaceutical Co., Ltd.

OPHLF
Ono Pharmaceutical Co., Ltd.US flagOther OTC
13.38
USD
-1.07
- -
6.29BMarket Cap
Ono Pharmaceutical Co., Ltd.
OPHLF
(Other OTC)

Recent

price

13.38

P/E

ratio

- -

div

yld

- -

ROIC.AI

2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
TTM
FRC
250.05
275.03
269.43
270.27
256.18
302.4
461.86
505.09
561.41
580.23
619.64
727.88
915.8
1,047.2
1,036.55
1,097.78
516.04
Revenue per Share
44.78
45.96
43.24
38.38
24.48
47.13
105.27
97
100.25
118.47
151.11
162.19
230.85
266.61
106.55
148.49
113.14
Basic EPS, GAAP
52.69
37
21.48
29.37
0.87
-2.34
95.04
-27.22
72.3
102.61
107.55
99.81
297.18
187.14
158.54
177.83
131.15
Free Cash Flow per Basic Share
36.15
35.95
35.95
35.99
35.96
35.96
37.95
45.17
42.46
45.19
44.98
55.73
60.91
77.46
79.87
79.88
40.47
Dividend per Share
837.27
888.15
891.09
894.11
881.23
887.38
961.46
920.82
1,004.52
1,075.38
1,200.69
1,333.67
1,489.35
1,636.49
1,720.8
1,803.67
1,714.07
Book Value per Share
727.68
763.73
799.33
809.47
832.65
826.24
903.69
914.18
971.91
995.26
1,144.89
1,202.4
1,389.88
1,544.36
930.32
1,022.49
891.15
Tangible Book Value per Share
541
530
530
530
530
530
530
518
514
504
499
496
488
480
470
470
473
Basic Weighted Avg Shares
135,255
145,778
142,806
143,247
135,775
160,284
244,797
261,836
288,634
292,420
309,284
361,361
447,187
502,672
486,871
515,785
243,960
Sales/Revenue/Turnover
26.03
26
20.96
18.45
10.9
19.03
29.53
23.18
21.48
26.5
31.79
28.56
31.75
31.82
12.27
17.88
25.78
Operating Margin (%)
3,051
3,005
4,765
5,109
6,100
6,534
7,821
9,213
10,621
14,214
15,820
17,721
17,451
18,140
26,894
37,752
9,054
Depreciation Expense
24,222
24,360
22,919
20,344
12,976
24,979
55,793
50,284
51,539
59,704
75,425
80,519
112,723
127,977
50,047
69,767
53,485
Net Income, GAAP
33.66
38.43
29.73
30.28
27.8
24.28
24.82
21.16
20.67
24.85
25.17
23.18
21.33
21.8
15.44
24.55
16.94
Effective Tax Rate (%)
17.91
16.71
16.05
14.2
9.56
15.58
22.79
19.2
17.86
20.42
24.39
22.28
25.21
25.46
10.28
13.53
21.92
Profit Margin (%)
165,172
155,488
170,497
167,285
162,868
171,379
188,100
140,995
111,467
133,893
153,909
215,340
222,172
309,972
306,808
304,663
276,750
Working Capital
12
222
484
468
317
515
542
320
1,765
6,173
7,030
6,501
6,678
6,552
113,500
82,468
128,788
LT Debt
394,572
424,841
442,541
451,724
475,213
476,255
524,211
529,618
562,736
568,022
639,743
661,674
747,813
798,605
788,202
856,644
788,110
Total Equity
5.72
5.58
4.76
4.07
2.27
4.78
10.51
8.79
8.78
9.89
11.64
11.83
15.26
15.43
5.71
7.15
5.86
Return on Invested Capital (%)
5.27
5.17
4.76
4.22
2.69
5.27
11.24
10.05
10.23
11.14
12.9
12.56
15.96
16.61
6.18
7.47
6.1
Return on Capital (%)
5.38
5.27
4.86
4.3
2.76
5.33
11.39
10.19
10.37
11.28
13.22
12.77
16.23
16.92
6.28
8.43
6.71
Return on Common Equity (%)

Capital Structure

FRC

in mil. unless spec.
Mar'24
Jun'25
Sep'25
ST Debt
2,310
- -
32,869
LT Borrowings
- -
- -
120,000
LT Finance Leases
6,552
- -
8,788
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
470
- -
470
Market Capitalization
1,209,113
1,067,710
991,444

Working Capital

FRC

in mil. unless spec.
Mar'24
Jun'25
Sep'25
Total Current Assets
413,596
- -
401,410
Cash, Cash Equivalents & STI
204,595
- -
181,134
Accounts Receivable, Net
136,066
- -
137,291
Inventories
48,629
- -
52,154
Total Current Liabilities
103,624
- -
124,660
Payables & Accruals
- -
- -
- -
ST Debt
2,310
- -
32,869
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
6.15%
6.12%
8.68%
Free Cash Flow
-446.85%
28.43%
12.2%
Net Income, GAAP
19.69%
7.76%
39.4%
Sales/Revenue/Turnover
13.28%
11.16%
5.94%
Total Cash Common Dividend
7.48%
11.34%
0.04%

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
120,016
138,697
131,191
112,769
502,672
2025
- -
- -
- -
- -
486,871
2026
- -
- -
- -
- -
515,785

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
65.16
88.18
75.77
- -
266.61
2025
- -
- -
- -
- -
106.55
2026
- -
- -
- -
- -
148.49

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
34.46
2.53
38.04
- -
77.46
2025
- -
- -
- -
- -
79.87
2026
- -
- -
- -
- -
79.88
Business
Ono Pharmaceutical Co., Ltd. (ticker: OPHLF) manufactures, procures, and markets prescription pharmaceuticals and diagnostic reagents worldwide, with a focus on oncology, immunology, neurology, and related therapeutic areas of unmet medical needs; core products include Opdivo (nivolumab) intravenous infusion for various cancers marketed in collaboration with Bristol Myers Squibb, BRAFTOVI (encorafenib) capsules for BRAF-mutated cancers, Qinlock (ripretinib) for gastrointestinal stromal tumors, ROMVIMZA (vimseltinib) for tenosynovial giant cell tumor, tirabrutinib hydrochloride for primary central nervous system lymphoma, landiolol hydrochloride for tachycardia, small molecule drugs, monoclonal antibodies, synthetic peptides, and bispecific antibodies targeting mechanisms such as LAG3 inhibitors, CSF-1R antagonists, BTK, PDGFRα, c-Kit, β1-adrenergic receptor, and BRAF V600E. Founded in 1717 and headquartered in Chuo-ku, Osaka, Japan, the company operates primarily in Japan, the United States, Europe, Asia, and Taiwan through subsidiaries including ONO PHARMA USA Inc., ONO PHARMA UK Ltd., and Deciphera Pharmaceuticals Inc., with major production facilities in Higashinari-ku Osaka and Fujinomiya Shizuoka, and a central research institute in Minase, Osaka. Recent developments include the June 2024 acquisition of Deciphera Pharmaceuticals for $2.4 billion to bolster its oncology pipeline and global commercial presence in the US and Europe, a February 2025 reorganization integrating Deciphera as the key hub for R&D and sales/marketing in those regions while ceasing certain UK R&D operations, US FDA approvals in 2025 for vimseltinib and various Opdivo combinations in colorectal cancer, hepatocellular carcinoma, and other indications, European Commission approvals for ROMVIMZA and subcutaneous Opdivo formulations, a June 2025 strategic agreement with Vertex for povetacicept development in Japan and South Korea, license agreements with Ionis for sapablursen and Seikagaku for Gel-One osteoarthritis treatment, research collaborations with Jorna Therapeutics and Reborna Biosciences for novel RNA editing and CNS therapeutics, and supplemental approvals in Japan and Asia for Opdivo-Yervoy combinations and BRAFTOVI in colorectal cancer.

Company News

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