Ono Pharmaceutical Co., Ltd.

Ono Pharmaceutical Co., Ltd.

OPHLF
Ono Pharmaceutical Co., Ltd.US flagOther OTC
14.55
USD
- -
- -
6.84BMarket Cap
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
2026 Y
TTM
Revenue per Share
270.27
256.18
302.4
461.86
505.09
561.41
580.23
619.64
727.88
915.8
1,047.2
1,036.55
- -
516.04
Basic EPS, GAAP
38.38
24.48
47.13
105.27
97
100.25
118.47
151.11
162.19
230.85
266.61
106.55
- -
113.14
Free Cash Flow per Basic Share
29.37
0.87
-2.34
95.04
-27.22
72.3
102.61
107.55
99.81
297.18
187.14
158.54
- -
131.15
Dividend per Share
35.99
35.96
35.96
37.95
45.17
42.46
45.19
44.98
55.73
60.91
77.46
79.87
- -
40.47
Book Value per Share
894.11
881.23
887.38
961.46
920.82
1,004.52
1,075.38
1,200.69
1,333.67
1,489.35
1,636.49
1,720.8
- -
1,714.07
Tangible Book Value per Share
809.47
832.65
826.24
903.69
914.18
971.91
995.26
1,144.89
1,202.4
1,389.88
1,544.36
930.32
- -
891.15
Basic Weighted Avg Shares
530
530
530
530
518
514
504
499
496
488
480
470
470
473
Sales/Revenue/Turnover
143,247
135,775
160,284
244,797
261,836
288,634
292,420
309,284
361,361
447,187
502,672
486,871
- -
243,960
Operating Margin (%)
18.45
10.9
19.03
29.53
23.18
21.48
26.5
31.79
28.56
31.75
31.82
12.27
- -
25.78
Depreciation Expense
5,109
6,100
6,534
7,821
9,213
10,621
14,214
15,820
17,721
17,451
18,140
26,894
- -
9,054
Net Income, GAAP
20,344
12,976
24,979
55,793
50,284
51,539
59,704
75,425
80,519
112,723
127,977
50,047
- -
53,485
Effective Tax Rate (%)
30.28
27.8
24.28
24.82
21.16
20.67
24.85
25.17
23.18
21.33
21.8
15.44
- -
16.94
Profit Margin (%)
14.2
9.56
15.58
22.79
19.2
17.86
20.42
24.39
22.28
25.21
25.46
10.28
- -
21.92
Working Capital
167,285
162,868
171,379
188,100
140,995
111,467
133,893
153,909
215,340
222,172
309,972
306,808
- -
276,750
LT Debt
468
317
515
542
320
1,765
6,173
7,030
6,501
6,678
6,552
113,500
- -
128,788
Total Equity
451,724
475,213
476,255
524,211
529,618
562,736
568,022
639,743
661,674
747,813
798,605
788,202
- -
788,110
Return on Invested Capital (%)
4.07
2.27
4.78
10.51
8.79
8.78
9.89
11.64
11.83
15.26
15.43
5.71
- -
5.86
Return on Capital (%)
4.22
2.69
5.27
11.24
10.05
10.23
11.14
12.9
12.56
15.96
16.61
6.18
- -
6.1
Return on Common Equity (%)
4.3
2.76
5.33
11.39
10.19
10.37
11.28
13.22
12.77
16.23
16.92
6.28
- -
6.71

Capital Structure

FRC

in mil. unless spec.
Mar'24
Jun'25
Sep'25
ST Debt
2,310
- -
32,869
LT Borrowings
- -
- -
120,000
LT Finance Leases
6,552
- -
8,788
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
470
- -
470
Market Capitalization
1,209,113
1,067,710
991,444

Working Capital

FRC

in mil. unless spec.
Mar'24
Jun'25
Sep'25
Total Current Assets
413,596
- -
401,410
Cash, Cash Equivalents & STI
204,595
- -
181,134
Accounts Receivable, Net
136,066
- -
137,291
Inventories
48,629
- -
52,154
Total Current Liabilities
103,624
- -
124,660
Payables & Accruals
- -
- -
- -
ST Debt
2,310
- -
32,869
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
- -
- -
Free Cash Flow
- -
- -
- -
Net Income, GAAP
- -
- -
- -
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
120,016
138,697
131,191
112,769
502,672
2025
- -
- -
- -
- -
486,871
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
65.16
88.18
75.77
- -
266.61
2025
- -
- -
- -
- -
106.55
2026
- -
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
34.46
2.53
38.04
- -
77.46
2025
- -
- -
- -
- -
79.87
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Gyo Sagara
Full Time Employees
3,853
Sector
Healthcare
Industry
Drug Manufacturers - General
Address
8-2, Kyutaromachi 1-chome Osaka Japan 541-8564
IPO Date
Mar 21, 2013
Business
Ono Pharmaceutical Co., Ltd. (ticker: OPHLF) manufactures, procures, and markets prescription pharmaceuticals and diagnostic reagents worldwide, with a focus on oncology, immunology, neurology, and related therapeutic areas of unmet medical needs; core products include Opdivo (nivolumab) intravenous infusion for various cancers marketed in collaboration with Bristol Myers Squibb, BRAFTOVI (encorafenib) capsules for BRAF-mutated cancers, Qinlock (ripretinib) for gastrointestinal stromal tumors, ROMVIMZA (vimseltinib) for tenosynovial giant cell tumor, tirabrutinib hydrochloride for primary central nervous system lymphoma, landiolol hydrochloride for tachycardia, small molecule drugs, monoclonal antibodies, synthetic peptides, and bispecific antibodies targeting mechanisms such as LAG3 inhibitors, CSF-1R antagonists, BTK, PDGFRα, c-Kit, β1-adrenergic receptor, and BRAF V600E. Founded in 1717 and headquartered in Chuo-ku, Osaka, Japan, the company operates primarily in Japan, the United States, Europe, Asia, and Taiwan through subsidiaries including ONO PHARMA USA Inc., ONO PHARMA UK Ltd., and Deciphera Pharmaceuticals Inc., with major production facilities in Higashinari-ku Osaka and Fujinomiya Shizuoka, and a central research institute in Minase, Osaka. Recent developments include the June 2024 acquisition of Deciphera Pharmaceuticals for $2.4 billion to bolster its oncology pipeline and global commercial presence in the US and Europe, a February 2025 reorganization integrating Deciphera as the key hub for R&D and sales/marketing in those regions while ceasing certain UK R&D operations, US FDA approvals in 2025 for vimseltinib and various Opdivo combinations in colorectal cancer, hepatocellular carcinoma, and other indications, European Commission approvals for ROMVIMZA and subcutaneous Opdivo formulations, a June 2025 strategic agreement with Vertex for povetacicept development in Japan and South Korea, license agreements with Ionis for sapablursen and Seikagaku for Gel-One osteoarthritis treatment, research collaborations with Jorna Therapeutics and Reborna Biosciences for novel RNA editing and CNS therapeutics, and supplemental approvals in Japan and Asia for Opdivo-Yervoy combinations and BRAFTOVI in colorectal cancer.

Company News

APIChat
  • Ono Pharma Announces Oral Presentation of New Data from the Phase 2 Clinical Study of ONO-4578 (EP4 antagonist) in Certain Gastric Cancers at the ASCO 2026 Annual Meeting

  • Ono Pharma Announces New Drug Discovery Collaboration with Congruence Therapeutics in the Priority Areas of Neurology and Immunology

  • Deciphera Pharmaceuticals Announces U.S. Food and Drug Administration Acceptance for Filing of New Drug Application for Tirabrutinib in Patients with Relapsed or Refractory PCNSL

  • Ono Pharmaceutical Co., Ltd. (OPHLY) Presents at 44th Annual J.P.

  • Ono Pharmaceutical Co., Ltd. (OPHLF) Q1 FY2025 Earnings Call Transcript

  • Ono Pharmaceutical Co., Ltd. (OPHLF) Q1 2024 Earnings Call Transcript

  • Japan's Ono Pharma says $2.4 bln Deciphera purchase 'first step' for global expansion

  • ONO to buy Deciphera Pharmaceuticals at a huge premium

  • ONO to buy Deciphera Pharmaceuticals at a huge premium

  • Deciphera Catapults 72% After Ono Pharmaceutical Agrees To Buy It For $2.4 Billion

  • Japan's ONO Pharmaceutical to buy Deciphera for $2.4 billion

  • Ono Pharmaceutical Co. (OPHLF) Upgraded to Buy: Here's Why