- CEO
- Michael Thyrring Engsig
- Full Time Employees
- 59
- Sector
- Health technology
- Industry
- Pharmaceuticals: major
- Address
- Oslo Research Park Oslo PS Norway 0349
- IPO Date
- Jun 16, 2022
- Business
- Nykode Therapeutics ASA (OSE: NYKD) is an Oslo-based clinical-stage biopharmaceutical company founded in 2006 that develops novel immunotherapies and vaccines based on its proprietary Vaccibody technology platform, which targets antigens to antigen-presenting cells to induce rapid, strong and long-lasting immune responses for treating cancers and infectious diseases. The company's lead wholly owned candidate, VB10.16, is an off-the-shelf therapeutic cancer immunotherapy in development for human papillomavirus type 16 (HPV16)-positive cancers including cervical, head and neck, and anal cancers; VB10.NEO is a proprietary individualized neoantigen immunotherapy in Phase 1b trials for locally advanced and metastatic solid tumors; additional programs target autoimmune diseases and infectious diseases through modular vaccine designs. Nykode Therapeutics operates primarily from its headquarters at Gaustadalléen 21 in Oslo, Norway, with a global development focus supported by clinical trials in Europe and the United States. Recent developments include the May 2024 expansion of its clinical trial collaboration and supply agreement with MSD (Merck & Co., Inc.) for a Phase 2 trial combining VB10.16 with KEYTRUDA (pembrolizumab) in HPV16-positive locally advanced cervical cancer patients undergoing chemoradiotherapy; ongoing discussions with Regeneron regarding a 2021 multi-target partnership covering three cancer vaccine and two infectious disease vaccine programs following preclinical asset adjustments; completion of a Roche collaboration Phase 2 trial in November 2023 evaluating VB10.16 with atezolizumab (Tecentriq) in recurrent or metastatic cervical cancer; and uplisting to the main list of the Oslo Stock Exchange to enhance visibility and access to capital markets.