- CEO
- Robert W. Overell
- Full Time Employees
- 10
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- 410 West Harrison Street Seattle WA United States of America 98119
- IPO Date
- May 18, 2016
- Business
- PhaseRx, Inc. (PZRXQ) operates as a biopharmaceutical company focused on developing mRNA-based therapies for inherited liver enzyme deficiencies, particularly urea cycle disorders in children; its pipeline includes PRX-OTC for ornithine transcarbamylase deficiency, PRX-ASL for argininosuccinate lyase deficiency, and PRX-ASS1 for argininosuccinate synthetase deficiency, leveraging proprietary Hybrid mRNA technology for intracellular enzyme replacement therapy. The company targets rare genetic diseases causing hyperammonemia and related neurological risks, with programs aimed at reinstating urea cycle function as an alternative to liver transplants. Founded in 2006 and headquartered in Seattle, Washington, PhaseRx serves pediatric patients globally through its research-stage operations. In December 2017, PhaseRx filed for voluntary Chapter 11 bankruptcy protection in the U.S. Bankruptcy Court for the District of Delaware, listing approximately $4.1 million in assets and $5.6 million in liabilities, amid cash constraints and Nasdaq delisting risks; the filing enabled exploration of strategic alternatives including asset sales. In February 2018, its assets were approved for sale to Roivant Sciences GmbH for $800,000 in cash plus debt assumption, though the deal was later cancelled in January 2019, leaving the company in a wind-down status with no active operations or recent developments reported as of 2025.