- CEO
- Timothy Dyer
- Full Time Employees
- 3
- Sector
- Health technology
- Industry
- Pharmaceuticals: major
- Address
- Chemin des Mines, 9 Geneva GE Switzerland 1202
- IPO Date
- May 22, 2007
- Business
- Addex Therapeutics Ltd, a clinical-stage biopharmaceutical company headquartered in Geneva, Switzerland and founded in 2002, discovers, develops and commercializes small-molecule allosteric modulators for neurological disorders; its lead product candidate dipraglurant, an mGlu5 negative allosteric modulator (NAM), advances in Phase 2a trials for Parkinson's disease levodopa-induced dyskinesia (PD-LID) and prepares for registration trials in PD-LID while also targeting post-stroke/TBI recovery and brain injury; ADX71149, an mGlu2 positive allosteric modulator (PAM), operates in Phase 2 readiness following rights regain from Janssen Pharmaceuticals for repositioning in mild neurocognitive disorders, schizophrenia and anxious depression; the preclinical pipeline encompasses GABAB PAM for pain, overactive bladder, substance use disorder (licensed to Indivior PLC) and chronic cough; mGlu7 NAM for post-traumatic stress disorder; mGlu2 NAM for treatment-resistant depression and cognitive deficits; mGlu4 PAM for Parkinson's disease; mGlu3 PAM for neurodegenerative disorders; and M4 PAM programs. The company conducts operations primarily from Switzerland with global partnerships and listings on the SIX Swiss Exchange (ADXN.SW) and Nasdaq (ADXN). In recent developments, Addex sold its allosteric modulator drug discovery platform and select preclinical programs to Neurosterix Pharma in April 2024, securing a 20% equity stake in the spin-out focused on schizophrenia, mood and neurocognitive therapies; regained full rights to ADX71149 after Janssen's 2025 discontinuation of the epilepsy program; entered a partnership with Sinntaxis for dipraglurant's brain injury indication; and reported CHF2.8 million in cash as of Q1 2025 to support pipeline advancement and new collaborations.