- CEO
- Yigong Shi
- Full Time Employees
- 29
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- 343 Phoenixville Pike Malvern PA United States of America 19355
- IPO Date
- Dec 12, 2013
- Business
- TetraLogic Pharmaceuticals Corporation TetraLogic Pharmaceuticals Corporation (TLOG) is a clinical-stage biopharmaceutical company that discovers, develops, and seeks to commercialize novel small molecule therapeutics targeting oncology and infectious diseases; its lead product candidates include birinapant, a SMAC mimetic that antagonizes inhibitor of apoptosis proteins to induce tumor cell death in hematological malignancies and solid tumors such as acute myeloid leukemia, pancreatic, and ovarian cancers, and SHAPE (suberohydroxamic acid phenyl ester), a proprietary topical histone deacetylase inhibitor for early-stage cutaneous T-cell lymphoma. The company maintains research collaborations, including with the Walter and Eliza Hall Institute of Medical Research on SMAC-mimetics like birinapant for infectious disease applications and past partnerships such as with Merck on birinapant combinations with pembrolizumab in solid tumors. Founded in 2001 and headquartered in Malvern, Pennsylvania, TetraLogic Pharmaceuticals Corporation previously known as Gentara Corporation until its name change in January 2006, acquired Shape Pharmaceuticals to expand its oncology pipeline with SHAPE and licensed birinapant assets to Medivir in 2016 amid clinical challenges, with its lead candidates now listed in discontinued or pending statuses across anemia, alopecia areata, and other indications as of recent pipeline updates.