Talphera, Inc.

Talphera, Inc.

TLPH
Talphera, Inc.US flagNASDAQ Global Market
0.77
USD
-0.01
- -
15.70MMarket Cap
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
14.84
2.4
8.7
7.66
3.41
0.74
0.58
1.27
0.47
- -
0.05
- -
- -
- -
Basic EPS, GAAP
-11.79
-15.36
-11.02
-19.05
-21.97
-16.14
-13.45
-9.47
-5.86
6.44
-1.29
-0.5
-0.34
-0.27
Free Cash Flow per Basic Share
-1.9
-18.4
-9.67
-14.62
-13.72
-10.24
-13.8
-9.47
-5.31
-3.89
-1.23
-0.49
-0.27
-0.21
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-73.17
-82.33
-91.72
-108.72
-127.05
-118.11
-100.53
-102.84
-79.02
-57.66
-31.14
-17.69
-11.12
-8.91
Tangible Book Value per Share
36.81
21.49
14.95
-2.36
-15.57
1.46
-10.46
-13.08
-5.99
1.76
0.37
-0.03
0.19
0.18
Basic Weighted Avg Shares
2
2
2
2
2
3
4
4
6
7
14
26
42
53
Sales/Revenue/Turnover
30
5
19
17
8
2
2
5
3
- -
1
- -
- -
- -
Operating Margin (%)
-22.6
-721.66
-99.66
-184.12
-483.83
-1,660.95
-2,368.06
-756.33
-1,276.26
- -
-2,594.32
- -
-48,157.14
-1,451,600
Depreciation Expense
1
1
2
2
2
1
2
2
2
2
- -
- -
- -
- -
Net Income, GAAP
-23
-33
-24
-43
-52
-47
-53
-40
-35
48
-18
-13
-14
-14
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
0.02
- -
- -
- -
- -
Profit Margin (%)
-79.4
-639.31
-126.66
-248.64
-644.25
-2,191.96
-2,325.91
-745.55
-1,245.53
- -
-2,825.96
- -
-51,035.71
-1,425,300
Working Capital
98
63
106
79
50
92
58
29
32
11
7
7
17
17
LT Debt
14
18
16
19
11
3
24
16
9
3
- -
- -
- -
- -
Total Equity
73
47
33
-5
-37
4
-41
-56
-36
22
14
8
17
18
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
-316.35
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
-11.2
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
- -
- -
- -
LT Borrowings
- -
- -
- -
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
46
49
50
Market Capitalization
29
48
40

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
22
21
21
Cash, Cash Equivalents & STI
21
20
21
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
3
4
4
Payables & Accruals
3
2
3
ST Debt
- -
- -
- -
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
-84.51%
-32.42%
112.91%
Free Cash Flow
-0.66%
-21.6%
-10.4%
Net Income, GAAP
-33.05%
-81.42%
9.89%
Sales/Revenue/Turnover
- -
- -
-95.7%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.16
-0.15
-0.13
-0.07
-0.5
2025
-0.1
-0.1
-0.11
-0.06
-0.34
2026
-0.04
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Vincent J. Angotti
Full Time Employees
13
Sector
Healthcare
Industry
Drug Manufacturers - Specialty & Generic
Address
1850 Gateway Drive San Mateo CA United States of America 94404
IPO Date
Feb 11, 2011
Business
Talphera, Inc. is a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for use in medically supervised settings. Its core product portfolio includes injectable ephedrine and phenylephrine prefilled syringes, marketed under the brand names Fedsyra™ and PFS-02 respectively, developed in partnership with France-based Laboratoire Aguettant to enhance safety and convenience in perioperative and acute-care settings. Talphera is also advancing Niyad™ (nafamostat mesylate), an anticoagulant in late-stage clinical development for use in continuous renal replacement therapy (CRRT) for critically ill patients, aiming for FDA PMA approval anticipated in the second half of 2026. The company’s products target hospital and acute care providers in North America and other markets, focusing on improving patient outcomes with innovative delivery formats and novel therapies. Talphera was founded in 2005 and is headquartered in Redwood City, California. The company underwent a strategic shift in 2023, renaming from AcelRx Pharmaceuticals to Talphera to reflect its broadened focus beyond acute pain products to a wider portfolio for medically supervised care. Recently, Talphera closed a $17 million financing round led by CorMedix, which includes rights for CorMedix to negotiate an acquisition following positive NEPHRO study results related to its nafamostat candidate. This financing supports the advancement of Niyad™ through to regulatory approval and commercialization. Talphera continues to expand clinical trial sites for its NEPHRO study with the goal of completing enrollment by the end of 2025. The company maintains a strong cash position and operational focus on delivering innovative pharmaceutical solutions that optimize clinical outcomes in critical care settings.

Company News

APIChat
  • Talphera, Inc. (TLPH) Q1 2026 Earnings Call Transcript

  • Talphera Announces First Quarter 2026 Financial Results and Provides Corporate Update

  • Talphera to Host First Quarter Financial Results and Corporate Update Call and Webcast on Wednesday, May 13, 2026

  • Talphera Announces Two Abstracts Accepted for Presentation at AKI & CRRT 2026

  • Talphera Q4 Earnings Call Highlights

  • Talphera, Inc. (TLPH) Analyst/Investor Day Transcript

  • Talphera Announces Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update

  • Talphera to Host Virtual Investor & Analyst Event to Discuss Niyad® for Use in Continuous Renal Replacement Therapy (CRRT), on March 23, 2026

  • Talphera Announces 50% Enrollment Milestone in Ongoing NEPHRO-CRRT Registrational Trial

  • Talphera (NASDAQ:TLPH) Insider Purchases $28,350.00 in Stock

  • Insider Buying: Talphera (NASDAQ:TLPH) Insider Acquires $28,350.00 in Stock

  • Insider Buying: Talphera (NASDAQ:TLPH) CFO Buys $36,450.00 in Stock

  • Talphera (NASDAQ:TLPH) Shares Down 0.3% – Here’s What Happened

  • Talphera (NASDAQ:TLPH) Stock Price Down 2.7% – Here’s Why

  • Talphera, Inc. (TLPH) Q3 2025 Earnings Call Transcript

  • Talphera Announces Third Quarter 2025 Financial Results and Provides Corporate Update

  • Talphera to Host Third Quarter Financial Results and Corporate Update Call and Webcast on Wednesday, November 12, 2025

  • Talphera, Inc. (NASDAQ:TLPH) Given Consensus Rating of “Buy” by Brokerages

  • Talphera Announces the Appointment of Joe Todisco to Board of Directors

  • CorMedix Announces Strategic Minority Investment in Talphera