OBI Pharma, Inc. (4174.TWO) is a clinical-stage global oncology company focused on developing novel cancer therapies including antibody-drug conjugates, therapeutic vaccines, and targeted prodrugs. Founded in 2002 and headquartered in Taipei, Taiwan, with subsidiaries in the United States and Australia, the company offers a pipeline featuring Adagloxad simolenin (Globo H-targeted vaccine in phase 3 for triple-negative breast cancer); OBI-833 (Globo H vaccine in phase 2 for non-small cell lung cancer); OBI-3424 (AKR1C3-targeted small-molecule prodrug in phase 2 for hepatocellular carcinoma and acute lymphocytic leukemia); OBI-992 and OBI-902 (TROP2-targeted ADCs in phase 1/2 for advanced solid tumors); OBI-999 (Globo H ADC); OBI-904 (Nectin-4 ADC); Trastuzumab-ADC (HER2-targeted); OBI-888 (Globo H monoclonal antibody); and bispecific ADCs in discovery, powered by proprietary GlycOBI, HYPrOBI, and ThiOBI enabling platforms for site-specific conjugation. OBI Pharma targets unmet needs in breast, ovarian, gastric, lung, liver, prostate, esophageal, and cholangiocarcinoma across global markets. Recent developments include US FDA Orphan Drug Designation for OBI-902 in cholangiocarcinoma (November 2025); initiation of phase 1/2 trials for OBI-902 (August 2025); technology collaboration with AP Biosciences for next-generation bispecific ADCs (September 2025); ADC partnership with TegMine Therapeutics utilizing GlycOBI and TegMiner technologies (June 2025); marketing agreement with GlyTech to expand GlycOBI outreach in Japan (December 2024); unveiling of ThiOBI and HYPrOBI platforms at AACR (April 2025); strategic pivot to prioritize ADC products and out-licensing following Globo H program termination (June 2025); and awards for most promising ADC clinical candidate and immunotherapy pipeline (March 2025).