Japan Tissue Engineering Co., Ltd. (7774.T) develops, manufactures and commercializes regenerative medicine products using tissue engineering technology in Japan. The company offers autologous cultured epidermis (JACE) for severe burns, congenital giant pigmented nevus and epidermolysis bullosa; autologous cultured cartilage (JACK) for traumatic cartilage defects, osteochondritis dissecans and knee osteoarthritis; autologous cultured corneal epithelium (EYE-01M) and autologous cultured oral mucosal epithelium (Ocural) for corneal epithelial stem cell deficiency; and autologous cultured epidermis maintaining melanocytes for vitiligo. It also provides contract development and manufacturing organization (CDMO) services, contract research organization (CRO) services, regulatory consulting and contract manufacturing of specific cell-processed products through its regenerative medicine outsourcing segment; and human cultured tissues for research purposes via its research and development support segment. Founded in 1999 and headquartered in Gamagori, Aichi, the company operates production facilities in Gamagori and serves medical institutions primarily in Japan as a subsidiary within the Teijin Group since 2021. Recent developments include expansion of JACK indications to knee osteoarthritis in May 2025; selection for government subsidies in July 2025 to expand regenerative medicine CDMO operations alongside Teijin Regenet Co.; a capital and business alliance with VCCT Inc. in December 2024 to accelerate commercialization of iPS cell-based retinal products; a research collaboration agreement with Sysmex Corporation in March 2025 on sterility testing for regenerative medicine and cell therapy; and insurance coverage for autologous cultured epidermis with melanocytes for vitiligo starting October 2024.