- Sector
- Healthcare
- Industry
- Biotechnology
- Address
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- IPO Date
- Jun 28, 2012
- Business
- Tesaro Inc. (TSRO), a wholly owned subsidiary of GlaxoSmithKline plc since its $5.1 billion acquisition completed in January 2019, operates as an oncology-focused biopharmaceutical company headquartered in Waltham, Massachusetts, and founded in 2010. The company develops and commercializes cancer therapeutics and supportive care products, including Zejula (niraparib), an oral poly ADP-ribose polymerase (PARP) inhibitor approved for ovarian cancer maintenance therapy regardless of BRCA status; Varubi (rolapitant), an intravenous NK-1 receptor antagonist for chemotherapy-induced nausea and vomiting; and Jemperli (dostarlimab), a PD-1 inhibitor approved for mismatch repair deficient recurrent or advanced endometrial cancer following platinum-based therapy. Its pipeline features immuno-oncology assets such as antibodies targeting TIM-3, LAG-3, and additional PARP inhibitors like stenoparib, which received FDA Fast Track designation in 2025 for advanced indications; operations span North America, Europe, and clinical development in global markets.
In recent developments, Tesaro initiated litigation in November 2025 against AnaptysBio Inc. in Delaware Chancery Court, alleging material breach of their 2014 collaboration agreement on Jemperli that could enable termination of the current license, acquisition of a perpetual license, and reduction of royalties and milestones by 50%; AnaptysBio countersued, escalating the dispute over contractual obligations. These legal actions represent the most significant recent operational changes for the GSK-integrated entity, amid ongoing advancements in its PARP inhibitor franchise and immuno-oncology portfolio.