- CEO
- Frank T. Weber
- Full Time Employees
- 16
- Sector
- Commercial services
- Industry
- Miscellaneous commercial services
- Address
- Weinbergweg 22 Halle SA Germany 06120
- IPO Date
- Oct 27, 2014
- Business
- Vivoryon Therapeutics N.V. (VVY.AS) is a clinical-stage biopharmaceutical company focused on developing innovative therapies targeting pathological toxic protein aggregation, primarily for Alzheimer's disease and other neurodegenerative disorders. The company offers a pipeline of small molecule inhibitors, including varoglutamstat (PQ912), a glutaminyl cyclase inhibitor in Phase 2 clinical trials for Alzheimer's disease; and HMTM (hydromethylthionine mesylate), an oral tau aggregation inhibitor advanced for Alzheimer's and Parkinson's disease treatment. Its research and development activities encompass discovery, preclinical studies, and clinical trials conducted through contract research organizations; services include biomarker development and patient stratification technologies based on proprietary pyroglutamate biomarkers. Vivoryon Therapeutics N.V., founded in 1997 and headquartered in Halle, Germany, operates primarily in Europe with clinical trial sites across multiple countries including Germany, the Netherlands, and Poland, targeting patients with neurodegenerative conditions through partnerships with academic institutions and contract manufacturers.
In recent developments, the company completed patient recruitment for its Phase 2 VIVIAD trial of varoglutamstat in early Alzheimer's disease in 2023, with topline data expected in the first half of 2025; it also initiated the Phase 2b MERIDIAN trial for Parkinson's disease in collaboration with global contract research organizations. Vivoryon announced a strategic pipeline prioritization in 2024, focusing resources on varoglutamstat while deprioritizing earlier-stage assets to extend cash runway into 2026 following a capital raise of approximately EUR 12 million through equity financing. No major acquisitions, name changes, or reorganizations have occurred in the last two years, with operations remaining centered on its core neurodegeneration franchise.