VYNE Therapeutics Inc.

VYNE Therapeutics Inc.

VYNE
VYNE Therapeutics Inc.US flagNASDAQ Global Select
0.89
USD
+0.08
- -
14.88MMarket Cap
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
4.21
16.02
35.35
- -
11.66
0.33
0.15
0.04
0.01
0.01
0.01
Basic EPS, GAAP
-28.75
-87.78
-101.65
-170.94
-222.79
-141.9
-25.64
-7.28
-2.77
-0.94
-0.62
-0.5
Free Cash Flow per Basic Share
-26.1
-14.33
-98.76
-175.68
-196.82
-76.18
-19.71
-9.17
-2.47
-0.8
-0.77
-0.6
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-100.12
-187.9
-206.93
-367.61
-557.22
-314.38
-223.66
-208.01
-67.3
-17.17
-17.72
-17.8
Tangible Book Value per Share
-99.54
-183.7
-199.39
433.21
207.09
20.82
17.01
9.79
8.64
1.22
0.65
0.58
Basic Weighted Avg Shares
- -
- -
- -
- -
- -
2
3
3
10
43
43
43
Sales/Revenue/Turnover
- -
1
5
11
- -
21
1
- -
- -
1
1
- -
Operating Margin (%)
- -
-2,126.41
-645.85
-512.55
- -
-540.54
-4,179.48
-7,189.73
-6,900.47
-8,709.98
-5,219.12
-5,367.62
Depreciation Expense
- -
- -
- -
- -
1
- -
- -
- -
- -
- -
- -
- -
Net Income, GAAP
-5
-14
-29
-51
-74
-256
-73
-23
-28
-40
-26
-21
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
- -
-2,087.24
-634.57
-483.51
- -
-1,217.4
-7,876.37
-4,865.83
-6,710.38
-7,950.9
-4,646.14
-4,726.21
Working Capital
43
28
56
130
68
65
45
29
88
50
28
25
LT Debt
- -
- -
- -
- -
- -
34
- -
- -
- -
- -
- -
- -
Total Equity
-16
-29
-57
130
69
37
49
31
89
52
28
25
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
- -
- -
- -
LT Borrowings
- -
- -
- -
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
32
33
33
Market Capitalization
14
25
26

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
36
30
26
Cash, Cash Equivalents & STI
33
29
25
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
4
2
1
Payables & Accruals
3
2
1
ST Debt
- -
- -
- -
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
-15.28%
18.05%
-46.69%
Free Cash Flow
121.76%
-17.73%
-2.83%
Net Income, GAAP
56.83%
-22.12%
-33.52%
Sales/Revenue/Turnover
- -
-24.7%
13.77%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
1
2025
- -
- -
- -
- -
1
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.15
-0.22
-0.29
-0.28
-0.94
2025
-0.2
-0.13
-0.17
- -
-0.62
2026
-0.08
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChatGPT
CEO
David T. Domzalski
Full Time Employees
10
Sector
Healthcare
Industry
Biotechnology
Address
P.O. Box 125 Stewartsville NJ United States of America 08807
IPO Date
Jan 25, 2018
Business
VYNE Therapeutics Inc. (Nasdaq: VYNE) is a clinical-stage biopharmaceutical company focused on developing differentiated therapies for chronic inflammatory and immunological conditions with high unmet medical needs. The company leverages its proprietary InhiBET platform to advance novel BET inhibitors, including its lead product candidate repibresib gel (VYN201), a topically administered pan-bromodomain and extra-terminal (BET) inhibitor soft drug designed for diseases involving diverse inflammatory cell signaling pathways with low systemic exposure, primarily targeting nonsegmental vitiligo; and VYN202, an oral BD2-selective small molecule BET inhibitor in Phase 1b trials for acute control and chronic management of immune-mediated inflammatory conditions such as moderate-to-severe plaque psoriasis. VYNE operates in the biotechnology sector, serving patients with autoimmune and immuno-inflammatory diseases through innovative topical and oral formulations. Founded in 2003 and headquartered in Bridgewater, New Jersey, the company conducts its clinical programs primarily in the United States. In recent developments, VYNE initiated a strategic review in August 2025 to explore options including partnerships, licensing, mergers, acquisitions, and asset sales to maximize shareholder value, engaging LifeSci Capital as financial advisor; the Phase 2b trial of repibresib gel in vitiligo missed primary endpoints, prompting trial termination and a search for an external development partner; and the FDA partially lifted a clinical hold on VYN202, enabling female enrollment while requiring additional toxicology data for males. Previously known as Menlo Therapeutics Inc., VYNE changed its name in September 2020 to reflect its focus on innovative immuno-inflammatory therapies.

Company News

APIChatGPT
  • VYNE Therapeutics Announces 1-for-50 Reverse Stock Split and Provides Update Regarding Special Dividend in Connection with the Proposed Merger with Yarrow Bioscience

  • VYNE Therapeutics Declares Special Cash Dividend in Connection with the Proposed Merger with Yarrow Bioscience

  • Short Interest in VYNE Therapeutics Inc. (NASDAQ:VYNE) Decreases By 35.7%

  • Contrasting Vivani Medical (NASDAQ:VANI) & VYNE Therapeutics (NASDAQ:VYNE)

  • VYNE Therapeutics Inc. (NASDAQ:VYNE) Short Interest Down 61.3% in February

  • Shareholder Alert: The Ademi Firm investigates whether VYNE Therapeutics Inc. is obtaining a Fair Price for its Public Shareholders

  • $HAREHOLDER ALERT: The M&A Class Action Firm Announces An Investigation of VYNE Therapeutics Inc. (NASDAQ: VYNE)

  • VYNE Therapeutics Inc. (VYNE) Yarrow Bioscience, Inc. - M&A Call Prepared Remarks Transcript

  • VYNE Stock Alert: Halper Sadeh LLC is Investigating Whether the Merger of VYNE Therapeutics Inc. is Fair to Shareholders

  • VYNE Therapeutics and Yarrow Bioscience Announce Merger Agreement

  • VYNE Therapeutics Inc. (VYNE) Reports Q3 Loss, Tops Revenue Estimates

  • VYNE Therapeutics Reports 2025 Third Quarter Financial Results and Provides Business Update

  • Savara (NASDAQ:SVRA) vs. VYNE Therapeutics (NASDAQ:VYNE) Critical Comparison

  • VYNE Therapeutics Inc. (VYNE) Reports Q2 Loss, Lags Revenue Estimates

  • VYNE Therapeutics Reports 2025 Second Quarter Financial Results and Provides Business Update

  • VYNE Therapeutics Announces Topline Results from Phase 2b Trial with Repibresib Gel in Nonsegmental Vitiligo

  • VYNE Therapeutics Provides Program Update on Oral BET inhibitor VYN202

  • VYNE Therapeutics Reports 2025 First Quarter Financial Results and Provides Business Update

  • FDA Puts VYNE Therapeutics Early-Stage Psoriasis Study On Hold

  • VYNE Therapeutics Provides Update on VYN202 Program