Xenetic Biosciences, Inc.

Xenetic Biosciences, Inc.

XBIO
Xenetic Biosciences, Inc.US flagNASDAQ Capital Market
2.70
USD
-0.11
- -
5.10MMarket Cap
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
330.47
- -
- -
48.45
105.04
- -
0.06
0.68
1.13
1.2
1.66
1.62
1.75
1.78
Basic EPS, GAAP
-2,835.18
-416.91
-355.34
-940.58
-49.78
-96.57
-63.31
-17.04
-5.49
-4.61
-2.71
-2.57
-1.58
-1.25
Free Cash Flow per Basic Share
-2,025.99
-371.27
-150.64
-142.18
20.56
-85.5
-22.43
-6.68
-4.61
-3.62
-2.69
-1.83
-1.34
-1.02
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-18,837.16
-2,199.33
-2,503.68
-2,298.56
-2,020.72
-2,026.86
-581.96
-276.73
-177.57
-132.94
-126.44
-127.94
-117.46
-111.8
Tangible Book Value per Share
-451.26
-79.82
-168.13
58.78
24.54
-34.61
27.93
19.11
17.89
9.59
6.41
3.9
4.35
3.88
Basic Weighted Avg Shares
- -
- -
- -
- -
- -
- -
- -
1
1
1
2
2
2
2
Sales/Revenue/Turnover
1
- -
- -
3
8
- -
- -
- -
1
2
3
3
3
3
Operating Margin (%)
-854.73
- -
- -
-1,581.02
-47.05
- -
-56,272.41
-1,074.41
-495.12
-393.57
-177.79
-168.16
-95.23
-75.05
Depreciation Expense
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Net Income, GAAP
-9
-14
-13
-54
-4
-7
-13
-11
-6
-7
-4
-4
-3
-2
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
-857.92
- -
- -
-1,806.87
-47.4
- -
-74,856.59
-2,493.11
-486.36
-383.87
-162.78
-158.39
-90.07
-70.03
Working Capital
2
- -
-3
6
4
- -
10
11
17
13
9
6
7
7
LT Debt
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Total Equity
13
10
7
16
14
10
17
12
18
14
10
6
7
7
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
- -
- -
- -
LT Borrowings
- -
- -
- -
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
2
2
2
Market Capitalization
5
3
5

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
5
8
8
Cash, Cash Equivalents & STI
4
8
7
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
1
1
1
Payables & Accruals
1
1
1
ST Debt
- -
- -
- -
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
12.8%
-3.8%
23.12%
Free Cash Flow
-67.12%
-10.15%
-18.84%
Net Income, GAAP
29.78%
-21.11%
-32.31%
Sales/Revenue/Turnover
- -
55.8%
19.04%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
1
1
1
1
3
2025
1
1
1
1
3
2026
1
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.78
-0.83
-0.28
- -
-2.57
2025
-0.59
-0.45
-0.33
- -
-1.58
2026
-0.2
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChatGPT
CEO
James F. Parslow
Full Time Employees
2
Sector
Healthcare
Industry
Biotechnology
Address
945 Concord Street Framingham MA United States of America 01701
IPO Date
Jun 30, 2016
Business
Xenetic Biosciences, Inc. (NASDAQ: XBIO) is a clinical-stage biopharmaceutical company focused on advancing innovative immune-oncology technologies to address hard-to-treat cancers, including pancreatic ductal adenocarcinoma, colorectal carcinoma, and other solid tumors. The company develops its proprietary DNase platform, which targets neutrophil extracellular traps (NETs) implicated in cancer progression, metastasis, and resistance to therapies such as chemotherapy, checkpoint inhibitors, immunotherapies, and CAR-T; its pipeline features XBIO-015 as a systemic DNase program for pancreatic carcinoma and locally advanced or metastatic solid tumors, and XBIO-020 for solid tumors, with ongoing preclinical proof-of-concept studies combining DNase I with chemotherapy, immunotherapy, and CAR-T across cancer models. It also maintains the PolyXen drug delivery platform, licensed exclusively to Takeda Pharmaceutical Co. Ltd. for blood coagulation disorders generating royalty revenue, alongside exploratory personalized CAR-T technology (XCART) targeting B-cell lymphomas. Founded in 1996 and headquartered in Framingham, Massachusetts, Xenetic operates primarily in the United States with global partnerships. Recent developments include a December 2024 Clinical Trial Services Agreement with PeriNess Ltd. to manage regulatory approvals and investigator-initiated studies of DNase I combined with chemotherapy/immunotherapy for pancreatic cancer and solid tumors in Israel, and a July 2025 Clinical Study Agreement via PeriNess for DNase I with anti-CD19 CAR-T in large B-cell lymphoma at Tel-Aviv Sourasky Medical Center; the company expanded its R&D collaboration with The Scripps Research Institute and Dr. Alexey Stepanov in July 2025 to include lymphoma/leukemia models, extending it by four months effective November 2025, completed preclinical studies advancing toward a Phase 1 trial, and raised approximately $3.9 million in net proceeds from a public offering in October 2025.

Company News

APIChatGPT
  • Xenetic Biosciences, Inc. Announces That Its Collaboration Partner Received Approval From the Israeli Ministry of Health to Conduct Exploratory, Investigator Initiated Study of DNase I In Combination With Anti-CD19 CAR T Cells in Large B-Cell Lymphoma

  • Xenetic Biosciences Showcases Compelling ASCO 2026 Data Demonstrating DNase I Significantly Enhances CAR-T Cell Persistence, Tumor Control, and Survival

  • Xenetic Biosciences Reports First Quarter 2026 Financial Results and Highlights Continued Advancement of DNase Oncology Platform

  • Xenetic Biosciences, Inc. Announces Abstract Acceptance for Presentation at the 2026 ASCO Annual Meeting

  • Klotho Neurosciences (NASDAQ:KLTO) and Xenetic Biosciences (NASDAQ:XBIO) Head to Head Contrast

  • Xenetic Biosciences, Inc. Reports Full Year 2025 Financial Results

  • Ainos (NASDAQ:AIMD) and Xenetic Biosciences (NASDAQ:XBIO) Head to Head Analysis

  • Xenetic Biosciences, Inc. (NASDAQ:XBIO) Sees Large Increase in Short Interest

  • Critical Contrast: Cumberland Pharmaceuticals (NASDAQ:CPIX) vs. Xenetic Biosciences (NASDAQ:XBIO)

  • Critical Review: Xenetic Biosciences (NASDAQ:XBIO) & Crinetics Pharmaceuticals (NASDAQ:CRNX)

  • Xenetic Biosciences, Inc. (NASDAQ:XBIO) Sees Large Drop in Short Interest

  • Xenetic Biosciences, Inc. Announces Adjournment of 2025 Annual Meeting

  • Xenetic Biosciences, Inc. Extends Research and Development Collaboration with Institute Investigator at Scripps Research to Advance DNase Platform

  • Xenetic Biosciences, Inc. Reports Third Quarter 2025 Financial Results

  • Xenetic Biosciences, Inc. Announces Pricing of $4.5 Million Underwritten Offering of Common Stock

  • Xenetic Biosciences, Inc. Reports Second Quarter 2025 Financial Results

  • Xenetic Biosciences (XBIO) Reports Q2 Loss, Misses Revenue Estimates

  • Xenetic Biosciences, Inc. Announces Entry by Collaboration Partner into Clinical Study Agreement to Advance Development of DNase Platform for the Treatment of Large B Cell Lymphoma

  • Xenetic Biosciences, Inc. Expands Research and Development Collaboration with The Scripps Research Institute to Advance DNase Platform

  • Xenetic Biosciences, Inc. Announces Update from Collaboration Partner of First Patient Dosed in Exploratory Clinical Study of DNase I in Combination with FOLFIRINOX for the First Line Treatment of Unresectable, Locally Advanced or Metastatic Pancreatic Cancer