Zentalis Pharmaceuticals, Inc.

Zentalis Pharmaceuticals, Inc.

ZNTL
Zentalis Pharmaceuticals, Inc.US flagNASDAQ Global Market
3.95
USD
-0.03
- -
281.19MMarket Cap
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
- -
- -
- -
- -
0.95
- -
- -
Basic EPS, GAAP
-1.17
-1.39
-4.19
-3.72
-4.48
-4.47
-2.33
- -
-1.74
Free Cash Flow per Basic Share
-1.36
-1.2
-3.12
-3.75
-3.15
-3.19
-2.41
- -
-1.76
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-1.94
-2.44
-7.14
-8.42
-11.28
-13.58
-14.83
- -
-17.17
Tangible Book Value per Share
-2.22
-2.61
11.41
8.45
8.14
6.63
4.74
- -
2.56
Basic Weighted Avg Shares
18
33
28
43
53
65
71
- -
71
Sales/Revenue/Turnover
- -
- -
- -
- -
- -
- -
67
- -
- -
Operating Margin (%)
-169,878.57
- -
- -
- -
- -
- -
-278.02
- -
- -
Depreciation Expense
- -
- -
- -
1
1
1
1
1
1
Net Income, GAAP
-21
-46
-118
-159
-237
-292
-166
-137
-124
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
-150,478.57
- -
- -
- -
- -
- -
-245.96
- -
- -
Working Capital
20
54
317
307
395
427
333
217
183
LT Debt
- -
- -
1
44
45
43
40
36
35
Total Equity
32
-73
333
364
434
437
337
216
183
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
- -
- -
- -
LT Borrowings
- -
- -
- -
LT Finance Leases
37
36
35
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
72
69
71
Market Capitalization
109
97
167

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
288
253
218
Cash, Cash Equivalents & STI
281
246
212
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
37
37
35
Payables & Accruals
37
37
35
ST Debt
- -
- -
- -
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
-5.92%
-35.88%
Free Cash Flow
- -
13.47%
-26.79%
Net Income, GAAP
- -
9.34%
-17.35%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
41
- -
- -
27
67
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
0.14
-1.24
-0.56
- -
-2.33
2025
-0.67
-0.37
-0.37
- -
- -
2026
-0.5
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Julie Eastland
Full Time Employees
166
Sector
Healthcare
Industry
Biotechnology
Address
1359 Broadway New York City NY United States of America 10018
IPO Date
Apr 3, 2020
Business
Zentalis Pharmaceuticals, Inc. (NASDAQ: ZNTL) is a clinical-stage biopharmaceutical company that discovers and develops small molecule therapeutics targeting fundamental biological pathways in cancer, with a primary focus on its lead candidate azenosertib (ZN-c3), a potentially first-in-class and best-in-class oral WEE1 inhibitor for advanced solid tumors including Cyclin E1-positive platinum-resistant ovarian cancer (PROC), uterine serous carcinoma (USC), PARP-resistant ovarian cancer, osteosarcoma, and BRAF V600E-mutated colorectal cancer; the company conducts ongoing Phase 2 monotherapy trials such as DENALI and TETON, Phase 1/2 combination studies with chemotherapy, PARP inhibitors, gemcitabine, and partners' agents like Pfizer's encorafenib and cetuximab, alongside a Phase 1 dose optimization study in solid tumors. Founded in 2014 and headquartered in San Diego, California, Zentalis operates primarily in the United States with a global clinical trial footprint targeting oncology patients in high-unmet-need segments. Recent developments include dosing the first patient in DENALI Part 2 registration-intent trial in April 2025 for Cyclin E1+ PROC with topline data anticipated by year-end 2026 and potential accelerated approval pathway, completion of TETON Phase 2 enrollment in USC with data planned for first-half 2026 amid prioritization of PROC, positive interim DENALI Part 1b data showing 34.9% objective response rate and 6.3-month median duration of response as of January 2025, a 2024 FDA partial clinical hold resolution on key azenosertib studies following sepsis cases, strategic leadership changes with CEO Julie Eastland and new CLO James Bucher appointed in 2025, and a cash position of $280.7 million as of Q3 2025 supporting operations into late 2027.

Company News

APIChat
  • Zentalis Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

  • Zentalis Strengthens Commercial Leadership with Appointments of Shannon Campbell to Board of Directors and Sarah Kelly as SVP of Commercial Strategy

  • Zentalis Pharmaceuticals to Present Phase 1b MUIR Trial Data Showing Encouraging Clinical Activity and Manageable Safety Profile of Azenosertib Plus Paclitaxel in Platinum-Resistant Ovarian Cancer at ASCO 2026

  • Zentalis Pharmaceuticals to Present Phase 1b MUIR Trial Data Showing Encouraging Clinical Activity and Manageable Safety Profile of Azenosertib Plus Paclitaxel in Platinum-Resistant Ovarian Cancer at ASCO 2026

  • Zentalis Pharmaceuticals to Participate in Upcoming Investor Conferences

  • Zentalis Pharmaceuticals Reports First Quarter 2026 Financial Results and Clinical Progress

  • Zentalis Pharmaceuticals Announces First Patient Dosed in ASPENOVA Phase 3 Trial of Azenosertib in Patients with Cyclin E1-Positive Platinum-Resistant Ovarian Cancer

  • Zentalis Pharmaceuticals Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

  • Zentalis Pharmaceuticals Announces Abstract Acceptance at ASCO 2026 Featuring Azenosertib in Combination with Paclitaxel for Platinum-Resistant Ovarian Cancer

  • Zentalis Pharmaceuticals To Present Azenosertib Preclinical Data in Triple-Negative Breast Cancer and Real-World Analysis of Unmet Need in Cyclin E1-Positive Ovarian Cancer at AACR 2026

  • What's Behind The Surge In Zentalis Stock?

  • Zentalis Pharmaceuticals Announces 400mg QD 5:2 Azenosertib Monotherapy as the Pivotal Study Dose in Cyclin E1-Positive Platinum-Resistant Ovarian Cancer

  • Zentalis Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

  • Zentalis Pharmaceuticals Reports Full Year 2025 Financial Results and Operational Updates

  • Zentalis Pharmaceuticals to Present Two Posters at the American Association for Cancer Research (AACR) Annual Meeting 2026

  • Zentalis Pharmaceuticals, Inc. $ZNTL Shares Sold by Almitas Capital LLC

  • Zentalis Pharmaceuticals to Participate in Upcoming Investor Conferences

  • Zentalis Pharmaceuticals Details Azenosertib Path to PROC Approval, DENALI Dose Pick Coming Soon

  • Zentalis Pharmaceuticals to Participate in Upcoming Investor Conference

  • Zentalis Pharmaceuticals Provides Corporate Update and Highlights Key Milestones and Expected Momentum in the Azenosertib Development Program for 2026